[HTML][HTML] Regulation of cholesterol homeostasis in health and diseases: From mechanisms to targeted therapeutics
Y Duan, K Gong, S Xu, F Zhang, X Meng… - Signal Transduction and …, 2022 - nature.com
Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …
Computational methods for the interaction between cyclodextrins and natural compounds: technology, benefits, limitations, and trends
B Ding, Y Yu, S Geng, B Liu, Y Hao… - Journal of Agricultural …, 2022 - ACS Publications
Cyclodextrins (CDs) have a hollow structure with a hydrophobic interior and hydrophilic
exterior. Forming inclusion complexes with CDs will maximize the bioavailability of natural …
exterior. Forming inclusion complexes with CDs will maximize the bioavailability of natural …
[HTML][HTML] HDL cholesterol levels and susceptibility to COVID-19
Background Host cell-membrane cholesterol, an important player in viral infections, is in
constant interaction with serum high-density lipoprotein-cholesterol (HDL-C) and low …
constant interaction with serum high-density lipoprotein-cholesterol (HDL-C) and low …
[HTML][HTML] Simvastatin downregulates the SARS-CoV-2-induced inflammatory response and impairs viral infection through disruption of lipid rafts
L Teixeira, JR Temerozo, FS Pereira-Dutra… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is currently a worldwide emergency caused by
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational clinical …
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational clinical …
Lancemaside A from Codonopsis lanceolata: Studies on antiviral activity and mechanism of action against SARS-CoV-2 and its variants of concern
Several plant-derived natural products with anti-SARS-CoV-2 activity have been evaluated
for the potential to serve as chemotherapeutic agents for the treatment of COVID-19 …
for the potential to serve as chemotherapeutic agents for the treatment of COVID-19 …
[HTML][HTML] SARS-CoV-2 employ BSG/CD147 and ACE2 receptors to directly infect human induced pluripotent stem cell-derived kidney podocytes
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the Coronavirus
disease 2019 (COVID-19), which has resulted in over 5.9 million deaths worldwide. While …
disease 2019 (COVID-19), which has resulted in over 5.9 million deaths worldwide. While …
[HTML][HTML] SARS-CoV-2, long COVID, prion disease and neurodegeneration
Y Zhao, VR Jaber, WJ Lukiw - Frontiers in Neuroscience, 2022 - frontiersin.org
On the last day of the year 2019 a novel Betacoronavirus (2019-nCov), now known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and causing the highly …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and causing the highly …
Low HDL Cholesterol Efflux Capacity Indicates a Fatal Course of COVID-19
JT Stadler, H Mangge, A Rani, P Curcic, M Herrmann… - Antioxidants, 2022 - mdpi.com
Plasma membrane cholesterol is required for proper trafficking and localization of receptors
that facilitate severe acute respiratory syndrome coronavirus 2 infection. High-density …
that facilitate severe acute respiratory syndrome coronavirus 2 infection. High-density …
[HTML][HTML] Giardial lipid rafts share virulence factors with secreted vesicles and participate in parasitic infection in mice
BI Grajeda, A De Chatterjee, CM Villalobos… - Frontiers in Cellular …, 2022 - frontiersin.org
Giardia lamblia, a protozoan parasite, is a major cause of waterborne infection, worldwide.
While the trophozoite form of this parasite induces pathological symptoms in the gut, the cyst …
While the trophozoite form of this parasite induces pathological symptoms in the gut, the cyst …
Veklury®(remdesivir) formulations inhibit initial membrane‐coupled events of SARS‐CoV‐2 infection due to their sulfobutylether‐β‐cyclodextrin content
Background and Purpose Despite its contradictory clinical performance, remdesivir
(Veklury®) has a pivotal role in COVID‐19 therapy. Possible contributions of the vehicle …
(Veklury®) has a pivotal role in COVID‐19 therapy. Possible contributions of the vehicle …