Current therapy for hypoplastic left heart syndrome and related single ventricle lesions

RG Ohye, D Schranz, Y D'Udekem - Circulation, 2016 - Am Heart Assoc
Universally fatal only 4 decades ago, the progress in the 3-stage palliation of hypoplastic left
heart syndrome and related single right ventricular lesions has drastically improved the …

The long-term management of children and adults with a Fontan circulation: a systematic review and survey of current practice in Australia and New Zealand

GK Gnanappa, DS Celermajer, GF Sholler, T Gentles… - Pediatric …, 2017 - Springer
Although long-term survival is now the norm, Fontan patients face significant morbidity and
premature mortality. Wide variation exists in long-term Fontan management. With an aim of …

Fibrinogen concentrate as an alternative to cryoprecipitate in a postcardiopulmonary transfusion algorithm in infants undergoing cardiac surgery: a prospective …

LA Downey, J Andrews, H Hedlin, K Kamra… - Anesthesia & …, 2020 - journals.lww.com
BACKGROUND: Infants undergoing cardiac surgery are at risk for bleeding and massive
transfusion due to an immature coagulation system, complex surgeries, and …

[HTML][HTML] Outcomes of heart transplantation in children with hypoplastic left heart syndrome previously palliated with the Norwood procedure

B Alsoufi, WT Mahle, C Manlhiot, S Deshpande… - The Journal of thoracic …, 2016 - Elsevier
Abstract Background Following the Norwood operation, unfavorable hemodynamic or
anatomic factors might disqualify children from progressing through subsequent palliative …

Mortality risk stratification in Fontan patients who underwent heart transplantation

CJ Berg, BS Bauer, A Hageman, JA Aboulhosn… - The American journal of …, 2017 - Elsevier
The number of patients who require orthotopic heart transplantation (OHT) for failing Fontan
physiology continues to grow; however, the methods and tools to evaluate risk of OHT are …

[HTML][HTML] The reality of limping to pediatric heart transplantation

KW Riggs, F Zafar, A Lorts, C Chin, R Bryant III… - The Journal of Thoracic …, 2020 - Elsevier
Objective Improvements in surgical technique, critical care, and early repair for congenital
heart disease (CHD) have led to improved outcomes with heart transplantation, often used …

Transplantation for congenital heart disease: focus on the impact of functionally univentricular versus biventricular circulation

KW Riggs, JT Broderick, N Price… - World Journal for …, 2021 - journals.sagepub.com
Background: Varying single center data exist regarding the posttransplant outcomes of
patients with single ventricle circulation, particularly following the Fontan operation. We …

Failures of the Fontan system in univentricular hearts and mortality risk in heart transplantation: a systematic review and meta-analysis

H Marquez-Gonzalez, JG Hernandez-Vasquez… - Life, 2021 - mdpi.com
The Fontan procedure (FP) is the standard surgical treatment for Univentricular heart
diseases. Over time, the Fontan system fails, leading to pathologies such as protein-losing …

In vivo evaluation of bioprinted cardiac patches composed of cardiac-specific extracellular matrix and progenitor cells in a model of pediatric heart failure

D Bejleri, MJ Robeson, ME Brown, J Hunter… - Biomaterials …, 2022 - pubs.rsc.org
Pediatric patients with congenital heart defects (CHD) often present with heart failure from
increased load on the right ventricle (RV) due to both surgical methods to treat CHD and the …

Modifiable risk factor reduction for pediatric ventricular assist devices and the influence of persistent modifiable risk factors at transplant

JW Greenberg, K Kulshrestha… - The Journal of Thoracic …, 2024 - Elsevier
Abstract Objectives Ventricular assist devices (VADs) are associated with a mortality benefit
in children. Database-driven analyses have associated VADs with reduction of modifiable …