[HTML][HTML] Differential Effects of n-3 and n-6 Polyunsaturated Fatty Acids on Placental and Embryonic Growth and Development in Diabetic Pregnant Mice

H Li, C Chen, S Liu, Y Shi, X Kuang, X Song, D Li, K Li - Nutrients, 2024 - mdpi.com
The present study aimed to investigate the differential effects of n-3 and n-6 polyunsaturated
fatty acids (PUFAs) on placental and embryonic development. Pregnant mice were assigned …

Dysregulation of DNA methylation and expression of imprinted genes in mouse placentas of fetal growth restriction induced by maternal cadmium exposure

P Xu, Z Wu, W Yang, L Wang - Toxicology, 2017 - Elsevier
Cadmium (Cd) is one of the most toxic environmental pollutants that cause fetal
malformation and growth restriction. However, the molecular mechanisms underlying …

Impact of inflammation and infection on the expression of amino acid transporters in the placenta: A minireview

ER McColl, M Hurtarte, M Piquette-Miller - Drug Metabolism and Disposition, 2022 - ASPET
Amino acid transporters expressed in the placenta help to regulate the transfer of amino
acids from maternal to fetal circulation. Nutritional or hormonal factors are known to …

[HTML][HTML] Single-cell analysis identifies thymic maturation delay in growth-restricted neonatal mice

WA Bacon, RS Hamilton, Z Yu, J Kieckbusch… - Frontiers in …, 2018 - frontiersin.org
Fetal growth restriction (FGR) causes a wide variety of defects in the neonate which can lead
to increased risk of heart disease, diabetes, anxiety and other disorders later in life …

[HTML][HTML] Placenta-Specific Transcripts Containing Androgen Response Elements Are Altered In Silico by Male Growth Outcomes

AS Meakin, M Smith, JL Morrison, CT Roberts… - International Journal of …, 2024 - mdpi.com
A birthweight centile (BWC) below the 25th is associated with an elevated risk of adverse
perinatal outcomes, particularly among males. This male vulnerability may stem from …

Placental insufficiency improves when intrauterine growth-restricted fetal sheep are administered daily ω-3 polyunsaturated fatty acid infusions

HN Beer, TA Lacey, RL Gibbs, MS Most… - Translational Animal …, 2021 - academic.oup.com
MATERIALS AND METHODS These studies were approved by the Institutional Animal Care
and Use Committee at the University of Nebraska-Lincoln, which is accredited by AAALAC …

Diet alters micronutrient pathways in the gut and placenta that regulate fetal growth and development in pregnant mice

E Palladino, T Van Mieghem, KL Connor - Reproductive Sciences, 2021 - Springer
Maternal malnutrition and micronutrient deficiencies can alter fetal development. However,
the mechanisms underlying these relationships are poorly understood. We used a systems …

Characterization of lipoproteins in human placenta and fetal circulation as well as gestational changes in lipoprotein assembly and secretion in human and mouse …

T Nargis, X Lin, E Giordano, L Ijaz, S Suhail… - … et Biophysica Acta (BBA …, 2023 - Elsevier
In the maternal circulation, apoB-containing low-density lipoproteins (LDL) and apoA1-
containing high-density lipoproteins (HDL) transport lipids. The production of lipoproteins in …

Placental mtDNA copy number and methylation in association with macrosomia in healthy pregnancy

XJ Lin, XX Xu, HX Zhang, MM Ding, WQ Cao, QY Yu… - Placenta, 2022 - Elsevier
Introduction Fetal growth and development depend on metabolic energy from placental
mitochondria. However, the impact of placental mitochondria on the occurrence of …

Downregulation of argininosuccinate synthase 1 (ASS1) is associated with hypoxia in placental development

S Fantone, L Ermini, F Piani, N Di Simone, G Barbaro… - Human Cell, 2023 - Springer
Argininosuccinate synthase (ASS1) is involved in nitric oxide production, which has a key
role in placental development improving pregnancy outcomes. Syncytiotrophoblast and …