In addition to clinical signs of infection (eg inflammation, purulence and pain), a microbial
count of≥ 105 colony‐forming units/g has historically been used to define wound infection …

This study tests the hypothesis that addition of a protease-modulating matrix enhances the
efficacy of autologous growth factors in diabetic ulcers. Fifty-one patients with chronic …

OBJECTIVE: Healthcare systems are being challenged to manage increasing numbers of
nonhealing wounds. Wound dressings are one of the first lines of defense in wound …

Excessive matrix metalloproteinase (MMP) levels have been observed in wound fluid of
impaired healing wounds. This is thought to interfere with granulation tissue formation as …

Venous leg ulcers (VLU s) are the most prevalent chronic wounds in western countries with
a heavy socioeconomic impact. Compression therapy is the etiologic treatment of VLU but …

Thrombin is the product of the hemostatic response essential to the conversion of fibrinogen
to fibrin. In addition, it is also responsible for the aggregation of blood platelets in the …

Chronic wounds represent a significant medical burden. Such wounds fail to normally
progress through the stages of healing, often complicated by a proinflammatory milieu …

Aims/hypothesis Foot ulcers in people with diabetes are a common and serious global
health issue. Dressings form a key part of ulcer treatment. Existing systematic reviews are …

Diabetic foot ulcers (DFU) are common, difficult-to-treat, and prone to complications. A
prospective, controlled study was conducted to: 1) examine the clinical efficacy of a …

Elderly diabetic patients are particularly burdened by foot disease. The main causes for foot
disease are peripheral neuropathy, foot deformities and peripheral arterial disease (PAD) …