Toll-like receptor-targeted anti-tumor therapies: Advances and challenges

Y Yang, H Li, C Fotopoulou, P Cunnea… - Frontiers in …, 2022 - frontiersin.org
Toll-like receptors (TLRs) are pattern recognition receptors, originally discovered to
stimulate innate immune reactions against microbial infection. TLRs also play essential roles …

Recent advances in treating female genital human papillomavirus related neoplasms with topical imiquimod

F Borella, N Gallio, L Mangherini… - Journal of Medical …, 2023 - Wiley Online Library
Human papillomavirus (HPV) encompasses a group of viruses that infect the skin and
mucous membranes. In the presence of certain factors, persistent infection with high‐risk …

“There is nothing that can prevent me from supporting her:” Men's perspectives on their involvement and support of women's use of topical therapy for cervical …

C Mungo, K Adewumi, E Adoyo, G Zulu… - Frontiers in …, 2024 - frontiersin.org
Purpose Cervical cancer disproportionately impacts women in low-and middle-income
countries (LMICs). The World Health Organization's (WHO) 90/70/90 strategy aims to …

Innovative diagnostic and therapeutic interventions in cervical dysplasia: a systematic review of controlled trials

JM Hecken, GA Rezniczek, CB Tempfer - Cancers, 2022 - mdpi.com
Simple Summary Cervical dysplasia is one of the most common disorders of the female
genital tract affecting millions of women worldwide. This systematic review of the literature of …

The efficacy of topical imiquimod in high‐grade cervical intraepithelial neoplasia: a systematic review and meta‐analysis

AJM Van De Sande, M Kengsakul… - … of Gynecology & …, 2024 - Wiley Online Library
Objective A major side effect of cervical excision for high‐grade cervical intraepithelial
neoplasia (CIN) is premature birth. A non‐invasive treatment for reproductive age women is …

Imiquimod for cervical and vaginal intraepithelial neoplasia: a systematic review and meta-analysis

Y Inayama, S Takamatsu, J Hamanishi… - Obstetrics & …, 2022 - journals.lww.com
OBJECTIVE: To evaluate the treatment efficacy and the risk of adverse events of imiquimod
for cervical intraepithelial neoplasia (CIN) and vaginal intraepithelial neoplasia (VAIN) …

Randomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine versus Observation in Patients with High-grade Pre-neoplastic Cervical Lesions …

SS Sheth, JE Oh, S Bellone, ER Siegel… - Clinical Cancer …, 2024 - AACR
Purpose: We report the results of a randomized phase II trial of imiquimod, a topical immune-
response modulator versus imiquimod plus a 9-valent human papillomavirus (HPV) vaccine …

[HTML][HTML] Topical imiquimod cream for the treatment of cervical intraepithelial neoplasia

HY Oo, SMM Lwin, AL Thu, K San Myint… - The Cochrane …, 2024 - ncbi.nlm.nih.gov
Topical imiquimod cream for the treatment of cervical intraepithelial neoplasia - PMC Back to
Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …

The role of TRL7/8 agonists in Cancer Therapy, with special emphasis on hematologic malignancies

M Leśniak, J Lipniarska, P Majka, W Kopyt, M Lejman… - Vaccines, 2023 - mdpi.com
Toll-like receptors (TLR) belong to the pattern recognition receptors (PRR). TLR7 and the
closely correlated TLR8 affiliate with toll-like receptors family, are located in endosomes …

[HTML][HTML] Immune Stimulation with Imiquimod to Best Face SARS-CoV-2 Infection and Prevent Long COVID

U Pacheco-García, E Varela-López… - International Journal of …, 2024 - mdpi.com
Through widespread immunization against SARS-CoV-2 prior to or post-infection, a
substantial segment of the global population has acquired both humoral and cellular …