Abstract Purpose of the Review The purpose of this review is to summarize recent evidence
supporting the use of reactive carbonyl species scavengers in the prevention and treatment …

Liver fibrosis is a common chronic hepatic disease. This study was done to examine the
effect of pyridoxamine against thioacetamide-induced hepatic fibrosis. Animals were divided …

Although the structural and functional effects of exercise on the heart are well established,
the metabolic changes that occur in the heart during and after exercise remain unclear. In …

Advanced glycation end products (AGEs) play a key role in the progression of heart failure.
Whether treatments limiting AGEs formation would prevent adverse left ventricular …

Acute kidney injury (AKI) is a common and independent risk factor for death and chronic
kidney disease (CKD). Despite promising preclinical data, there is no evidence that …

Age-related increases in large artery stiffness are associated with cerebrovascular
dysfunction and cognitive impairment. Pyridoxamine treatment prevents large artery …

Background Myocardial injury after noncardiac surgery (MINS) is one of the most common
complications associated with postoperative adverse cardiovascular outcomes and …

Changes in vascular mechanics due to aging include elevated vascular impedance,
diminished aorta distensibility, and an accelerated return of pulse wave reflection, which …

Regular aerobic exercise promotes physiological cardiac growth, which is an adaptive
response thought to enable the heart to meet higher physical demands. Cardiac growth …

Cardiovascular aging in humans is accompanied by fundamental biochemical, metabolic,
and molecular changes that ultimately result in basal dysfunction and increased …