Adverse drug reactions (ADRs) account for a large proportion of hospitalizations among
adults and are more common in multimorbid patients, worsening clinical outcomes and …

Oral anticoagulants are required for both treatment and prophylaxis in many different
diseases. Clinicians and patients now have a choice of oral anticoagulants, including the …

It is estimated that the total annual financial cost for pain management in the US exceeds
100 billion dollars. However, when indirect costs are included, such as functional disability …

Schizophrenia (SCZ) is a complex psychiatric disorder of multifactorial origin, in which both
genetic and environmental factors have an impact on its onset, course, and outcome. Large …

The clinical implementation of pharmacogenetics (the study of how genetics influence
individual variations in drug response) is a key factor in the development of programmes to …

It has been reported that only 30% of patients use psychopharmacological treatment with
perceived clinical success (SBU rapport Swedish Research Council, 2004; Walker et al …

Opioids are extensively used in patients with cancer pain; despite their efficacy, several
patients can experience ineffective analgesia and/or side effects. Pharmacogenetics is a …

Depression leads the higher personal and socio-economical burden within psychiatric
disorders. Despite the fact that over 40 antidepressants (ADs) are available, suboptimal …

Objective Pharmacogenomics (PGx) is a clinically significant factor in the safe and
efficacious use of medicines. While PGx knowledge is abundant for other populations, there …

For~ 80 drugs, widely recognized pharmacogenetics dosing guidelines are available.
However, the use of these guidelines in clinical practice remains limited as only a fraction of …