[HTML][HTML] Cerebral edema formation after stroke: emphasis on blood–brain barrier and the lymphatic drainage system of the brain
S Chen, L Shao, L Ma - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Brain edema is a severe stroke complication that is associated with prolonged
hospitalization and poor outcomes. Swollen tissues in the brain compromise cerebral …
hospitalization and poor outcomes. Swollen tissues in the brain compromise cerebral …
Response of the cerebral vasculature following traumatic brain injury
The critical role of the vasculature and its repair in neurological disease states is beginning
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …
Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis
Aquaporin channels facilitate bidirectional water flow in all cells and tissues. AQP4 is highly
expressed in astrocytes. In the CNS, it is enriched in astrocyte endfeet, at synapses, and at …
expressed in astrocytes. In the CNS, it is enriched in astrocyte endfeet, at synapses, and at …
Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury
JJ Iliff, MJ Chen, BA Plog, DM Zeppenfeld… - Journal of …, 2014 - Soc Neuroscience
Traumatic brain injury (TBI) is an established risk factor for the early development of
dementia, including Alzheimer's disease, and the post-traumatic brain frequently exhibits …
dementia, including Alzheimer's disease, and the post-traumatic brain frequently exhibits …
[HTML][HTML] Mechanisms of blood–brain barrier dysfunction in traumatic brain injury
A Cash, MH Theus - International journal of molecular sciences, 2020 - mdpi.com
Traumatic brain injuries (TBIs) account for the majority of injury-related deaths in the United
States with roughly two million TBIs occurring annually. Due to the spectrum of severity and …
States with roughly two million TBIs occurring annually. Due to the spectrum of severity and …
Physiological roles of aquaporin-4 in brain
EA Nagelhus, OP Ottersen - Physiological reviews, 2013 - journals.physiology.org
Aquaporin-4 (AQP4) is one of the most abundant molecules in the brain and is particularly
prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While …
prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While …
[HTML][HTML] Aquaporin 4: a player in cerebral edema and neuroinflammation
Neuroinflammation is a common pathological event observed in many different brain
diseases, frequently associated with blood brain barrier (BBB) dysfunction and followed by …
diseases, frequently associated with blood brain barrier (BBB) dysfunction and followed by …
Aquaporin and brain diseases
Background The presence of water channel proteins, aquaporins (AQPs), in the brain led to
intense research in understanding the underlying roles of each of them under normal …
intense research in understanding the underlying roles of each of them under normal …
[PDF][PDF] New insights into coupling and uncoupling of cerebral blood flow and metabolism in the brain
The brain's high energy requirements and limited storage capacity make persistent cerebral
blood flow (CBF) critical for its proper functioning as well as for the prevention of damage …
blood flow (CBF) critical for its proper functioning as well as for the prevention of damage …
White matter damage and glymphatic dysfunction in a model of vascular dementia in rats with no prior vascular pathologies
We investigated cognitive function, axonal/white matter (WM) changes and glymphatic
function of vascular dementia using a multiple microinfarction (MMI) model in retired breeder …
function of vascular dementia using a multiple microinfarction (MMI) model in retired breeder …