Traumatic brain injury (TBI) is among the most pressing global health issues and prevalent
causes of cerebrovascular and neurological disorders all over the world. In addition to the …

Brain edema is a common feature of brain injuries, which leads to increased intracranial
pressure (ICP) and ischemia that worsen outcome. Current management of edema focuses …

We investigated cognitive function, axonal/white matter (WM) changes and glymphatic
function of vascular dementia using a multiple microinfarction (MMI) model in retired breeder …

Stroke is a complex and devastating neurological condition with limited treatment options.
Brain edema is a serious complication of stroke. Early edema formation can significantly …

In the past, water homeostasis of the brain was understood as a certain quantitative
equilibrium of water content between intravascular, interstitial, and intracellular spaces …

In the past, the neuron has been the focal point of brain injury research. However, in recent
years, the pathophysiology of the blood-brain barrier (BBB) has become increasingly more …

Disorders of the developing brain represent a major health problem. The neurological
manifestations of brain lesions can range from severe clinical deficits to more subtle …

Since its introduction in the early 1990s, diffusion-weighted magnetic resonance imaging
(MRI) has played a crucial role in the non-invasive evaluation of tissue microstructure of …

Senile plaques (SPs) containing amyloid β peptide (Aβ) 1–42 are the major species present
in Alzheimer disease (AD), whereas Aβ1–40 is the major constituent of arteriolar walls …

A hallmark of stroke is water accumulation (edema) resulting from dysregulation of osmotic
homeostasis. Brain edema contributes to tissue demise and may lead to increased …