Aging refers to the gradual physiological changes that occur in an organism after reaching
adulthood, resulting in senescence and a decline in biological functions, ultimately leading …

An increase in life expectancy in developed countries has led to a surge of chronic aging-
related diseases. In the last few decades, several studies have provided evidence of the …

Senescence drives organismal aging, yet the deep characterization of senescent cells in
vivo remains incomplete. Here, we apply mass cytometry by time-of-flight using carefully …

Aging is the result of a gradual functional decline at the cellular, and ultimately, organismal
level, resulting in an increased risk of developing a variety of chronic illnesses, such as …

Senescent cells (SnCs) are implicated in aging and various age‐related pathologies.
Targeting SnCs can treat age‐related diseases and extend health span. However, precisely …

Population aging, a pervasive global demographic trend, is anticipated to challenge health
and social systems worldwide. This phenomenon is due to medical advancements enabling …

Aging results in systemic changes that leave older adults at much higher risk for adverse
outcomes following respiratory infections. Much work has been done over the years to …

Accumulating evidence indicates that the increased burden of senescent cells (SCs) in aged
organisms plays an important role in many age-associated diseases. The pharmacological …

Oxidative stress can upset the antioxidant balance and cause accelerated aging including
neurodegenerative diseases and decline in physiological function. Therefore, an antioxidant …

Aging is the main risk factor for cardiovascular disease (CVD). As the world's population
ages rapidly and CVD rates rise, there is a growing need for physiologically relevant models …