HE4 as a Biomarker for Endometrial Cancer
R Behrouzi, CE Barr, EJ Crosbie - Cancers, 2021 - mdpi.com
Simple Summary There are currently no blood biomarkers approved for routine clinical use
in endometrial cancer. Serum human epididymis protein 4 (HE4) is significantly higher in …
in endometrial cancer. Serum human epididymis protein 4 (HE4) is significantly higher in …
Urinary biomarkers and their potential for the non-invasive detection of endometrial cancer
K Njoku, D Chiasserini, ER Jones, CE Barr… - Frontiers in …, 2020 - frontiersin.org
Endometrial cancer is the most common malignancy of the female genital tract and its
incidence is rising in parallel with the mounting prevalence of obesity. Early diagnosis has …
incidence is rising in parallel with the mounting prevalence of obesity. Early diagnosis has …
Upgrading Treatment and Molecular Diagnosis in Endometrial Cancer—Driving New Tools for Endometrial Preservation?
One emerging problem for onco-gynecologists is the incidence of premenopausal patients
under 40 years of age diagnosed with stage I Endometrial Cancer (EC) who want to …
under 40 years of age diagnosed with stage I Endometrial Cancer (EC) who want to …
Proteomic biomarkers for the detection of endometrial cancer
Endometrial cancer is the leading gynaecological malignancy in the western world and its
incidence is rising in tandem with the global epidemic of obesity. Early diagnosis is key to …
incidence is rising in tandem with the global epidemic of obesity. Early diagnosis is key to …
[HTML][HTML] The emerging role of HE4 in the evaluation of advanced epithelial ovarian and endometrial carcinomas
AR Simmons, K Baggerly, RC Bast Jr - Oncology (Williston Park …, 2013 - ncbi.nlm.nih.gov
Abstract HE4 (human epididymis protein 4) is overexpressed in both ovarian and
endometrial cancers. Levels of the shed HE4 protein are elevated in sera from ovarian and …
endometrial cancers. Levels of the shed HE4 protein are elevated in sera from ovarian and …
HE4 tissue expression and serum HE4 levels in healthy individuals and patients with benign or malignant tumors: a systematic review
NS Karlsen, MA Karlsen, CK Høgdall… - … , Biomarkers & Prevention, 2014 - AACR
Abstract Human epididymis protein 4 (HE4) has received major attention as a potential
tumor marker in epithelial ovarian cancer; however, evidence of significant overexpression …
tumor marker in epithelial ovarian cancer; however, evidence of significant overexpression …
Ovarian cancer recurrence and early detection: may HE4 play a key role in this open challenge? A systematic review of literature
S Capriglione, D Luvero, F Plotti, C Terranova… - Medical Oncology, 2017 - Springer
Despite the improvement in overall survival for ovarian cancer (OC) patients, a fraction of
patients with advanced-stage disease fails to respond to primary therapy and relapses in …
patients with advanced-stage disease fails to respond to primary therapy and relapses in …
HE 4 and CA 125 levels in the preoperative assessment of endometrial cancer patients: a prospective multicenter study (ENDOMET)
SL Antonsen, E Høgdall, IJ Christensen… - Acta obstetricia et …, 2013 - Wiley Online Library
Objective To evaluate whether human epididymis protein 4 (HE 4) and CA 125 correlate
with known high‐risk prognostic factors for endometrial cancer. Design Prospective …
with known high‐risk prognostic factors for endometrial cancer. Design Prospective …
Discovery of biomarkers for endometrial cancer: current status and prospects
TL Rižner - Expert review of molecular diagnostics, 2016 - Taylor & Francis
Introduction: Endometrial cancer is the most frequent gynecological malignancy in the
developed world. Currently, endometrial histology is the gold standard for diagnosis, as …
developed world. Currently, endometrial histology is the gold standard for diagnosis, as …
Can the preoperative HE4 level predict optimal cytoreduction in patients with advanced ovarian carcinoma?
R Angioli, F Plotti, S Capriglione, A Aloisi… - Gynecologic …, 2013 - Elsevier
OBJECTIVE: Optimal surgical outcome has been proved to be one of the most powerful
survival determinants in the management of ovarian cancer patients. Actually, for ovarian …
survival determinants in the management of ovarian cancer patients. Actually, for ovarian …