[HTML][HTML] Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

OXA β-lactamases

BA Evans, SGB Amyes - Clinical microbiology reviews, 2014 - Am Soc Microbiol
The OXA β-lactamases were among the earliest β-lactamases detected; however, these
molecular class D β-lactamases were originally relatively rare and always plasmid …

Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?

A Beceiro, M Tomás, G Bou - Clinical microbiology reviews, 2013 - Am Soc Microbiol
Hosts and bacteria have coevolved over millions of years, during which pathogenic bacteria
have modified their virulence mechanisms to adapt to host defense systems. Although the …

[HTML][HTML] Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside

MF Lin, CY Lan - World Journal of Clinical Cases: WJCC, 2014 - ncbi.nlm.nih.gov
Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

Global evolution of multidrug-resistant Acinetobacter baumannii clonal lineages

R Zarrilli, S Pournaras, M Giannouli… - International journal of …, 2013 - Elsevier
The rapid expansion of Acinetobacter baumannii clinical isolates exhibiting resistance to
carbapenems and most or all available antibiotics during the last decade is a worrying …

“Stormy waters ahead”: global emergence of carbapenemases

G Patel, RA Bonomo - Frontiers in microbiology, 2013 - frontiersin.org
Carbapenems, once considered the last line of defense against of serious infections with
Enterobacteriaceae, are threatened with extinction. The increasing isolation of carbapenem …

The Acinetobacter baumannii Oxymoron: Commensal Hospital Dweller Turned Pan-Drug-Resistant Menace

I Roca, P Espinal, X Vila-Farrés, J Vila - Frontiers in microbiology, 2012 - frontiersin.org
During the past few decades Acinetobacter baumannii has evolved from being a commensal
dweller of health-care facilities to constitute one of the most annoying pathogens …

Insights into the global molecular epidemiology of carbapenem non-susceptible clones of Acinetobacter baumannii

N Karah, A Sundsfjord, K Towner… - Drug Resistance Updates, 2012 - Elsevier
The global emergence of multidrug resistance (MDR) among Gram-negative bacteria has
dramatically limited the therapeutic options. During the last two decades, Acinetobacter …

[HTML][HTML] Molecular characterization of carbapenem-insensitive Acinetobacter baumannii in Egypt

MH Al-Agamy, NG Khalaf, MM Tawfick, AM Shibl… - International Journal of …, 2014 - Elsevier
Objectives This study investigated the prevalence of diverse Ambler class β-lactamase-
encoding genes in 40 carbapenem-insensitive Acinetobacter baumannii isolates collected …

Phenotypic and genotypic characterization of carbapenem-resistant Acinetobacter baumannii isolates from Egypt

A Abouelfetouh, AS Torky, E Aboulmagd - Antimicrobial Resistance & …, 2019 - Springer
Background Antibiotic use is largely under-regulated in Egypt leading to the emergence of
resistant isolates. Carbapenems are last resort agents to treat Acinetobacter baumannii …