Kidney stone, one of the oldest known diseases, has plagued humans for centuries,
consistently imposing a heavy burden on patients and healthcare systems worldwide due to …

Chronic kidney disease (CKD) is a major worldwide public health problem. The increase in
the number of patients with CKD and end-stage kidney disease requesting renal dialysis or …

Background Periodontitis is an inflammatory disease characterized by inflammation and
progressive destruction of periodontal tissues including alveolar bone. α-klotho protein is a …

Background Renal interstitial fibrosis (RIF) is the main pathological feature of end-stage
renal disease (ESRD) caused by various chronic kidney diseases (CKD), and is closely …

As a common malignant tumor among women, ovarian cancer poses a serious threat to their
health. This study demonstrates that long non-coding RNA NRSN2-AS1 is over-expressed …

Introduction: Kidney stones (KSs) are associated with hematuria and renal failure and pose
a significant clinical and public health concern. Diabetes is associated with a higher risk of …

Background Randall's plaques (RP) are identified as anchored sites for kidney calcium
oxalate stones, but the mechanism remains unclear. Given the importance of osteogenic-like …

Randall's plaque (RP) is derived from interstitial mineral deposition and is highly prevalent
in renal calcium oxalate (CaOx) stone disease, which is predictive of recurrence. This study …

AKI (acute kidney injury) with maladaptive repair plays exacerbated role in renal fibrosis
characterized by tubulointerstitial fibrosis. Previously, we reported that IKKα contributed to …

As a common malignant tumor among women, ovarian cancer poses a serious threat to their
health. This study demonstrates that long non-coding RNA NRSN2-AS1 is over-expressed …