[HTML][HTML] Expression patterns and miRNA regulation of DNA methyltransferases in chicken primordial germ cells
DNA methylation is widespread in most species, from bacteria to mammals, and is crucial for
genomic imprinting, gene expression, and embryogenesis. DNA methylation occurs via two …
genomic imprinting, gene expression, and embryogenesis. DNA methylation occurs via two …
Cytosine modifications in neurodevelopment and diseases
DNA methylation has been studied comprehensively and linked to both normal
neurodevelopment and neurological diseases. The recent identification of several new DNA …
neurodevelopment and neurological diseases. The recent identification of several new DNA …
[HTML][HTML] Convolutional neural network transformer (CNNT) for fluorescence microscopy image denoising with improved generalization and fast adaptation
A Rehman, A Zhovmer, R Sato, Y Mukouyama… - Scientific Reports, 2024 - nature.com
Deep neural networks can improve the quality of fluorescence microscopy images. Previous
methods, based on Convolutional Neural Networks (CNNs), require time-consuming training …
methods, based on Convolutional Neural Networks (CNNs), require time-consuming training …
UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis
Ubiquitin-like, containing PHD and RING finger domains 1 (uhrf1) is regulated at the
transcriptional level during the cell cycle and in developing zebrafish embryos. We identify …
transcriptional level during the cell cycle and in developing zebrafish embryos. We identify …
[HTML][HTML] Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes
YT Chen, JW Liao, YC Tsai, FJ Tsai - Oncotarget, 2016 - ncbi.nlm.nih.gov
Our previous genome-wide association studies showed that DNA methyltransferase 1
(DNMT1) is associated with increased susceptibility to type 2 diabetes (T2D) in Han Chinese …
(DNMT1) is associated with increased susceptibility to type 2 diabetes (T2D) in Han Chinese …
Expression of the dnmt3 genes in zebrafish development: similarity to Dnmt3a and Dnmt3b
THL Smith, TM Collins, RA McGowan - Development genes and evolution, 2011 - Springer
The zebrafish differs from mammals in that they have six dnmt3 genes as opposed to the two
that can produce a catalytically active protein in mammals. Zebrafish also do not show …
that can produce a catalytically active protein in mammals. Zebrafish also do not show …
[HTML][HTML] Epigenetic factors Dnmt1 and Uhrf1 coordinate intestinal development
Intestinal tract development is a coordinated process involving signaling among the
progenitors and developing cells from all three germ layers. Development of endoderm …
progenitors and developing cells from all three germ layers. Development of endoderm …
[HTML][HTML] dnmt1 function is required to maintain retinal stem cells within the ciliary marginal zone of the zebrafish eye
KM Angileri, JM Gross - Scientific Reports, 2020 - nature.com
The ciliary marginal zone (CMZ) of the zebrafish retina contains a population of actively
proliferating resident stem cells, which generate retinal neurons throughout life. The …
proliferating resident stem cells, which generate retinal neurons throughout life. The …
Ultraviolet B inhibition of DNMT1 activity via AhR activation dependent SIRT1 suppression in CD4+ T cells from systemic lupus erythematosus patients
Z Wu, X Mei, Z Ying, Y Sun, J Song, W Shi - Journal of Dermatological …, 2017 - Elsevier
Background Previous studies have reported that ultraviolet B (UVB) inhibits DNA
methyltransferase1 (DNMT1) activity in CD4+ T cells from systemic lupus erythematosus …
methyltransferase1 (DNMT1) activity in CD4+ T cells from systemic lupus erythematosus …
Chromatin regulators in pancreas development and diabetes
SA Campbell, BG Hoffman - Trends in Endocrinology & Metabolism, 2016 - cell.com
The chromatin landscape of a cell is dynamic and can be altered by chromatin regulators
that control nucleosome placement and DNA or histone modifications. Together with …
that control nucleosome placement and DNA or histone modifications. Together with …