[HTML][HTML] SARS-CoV-2, COVID-19 and the aging immune system
JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …
particular risk for severe disease and death in older adults and in adults with age-related …
[HTML][HTML] Patients with COVID-19: in the dark-NETs of neutrophils
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
[HTML][HTML] Genetic mechanisms of critical illness in COVID-19
Host-mediated lung inflammation is present, and drives mortality, in the critical illness
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …
[HTML][HTML] NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond
Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …
Neutrophil, neutrophil extracellular traps and endothelial cell dysfunction in sepsis
H Zhang, Y Wang, M Qu, W Li, D Wu… - Clinical and …, 2023 - Wiley Online Library
Sepsis is a persistent systemic inflammatory condition involving multiple organ failures
resulting from a dysregulated immune response to infection, and one of the hallmarks of …
resulting from a dysregulated immune response to infection, and one of the hallmarks of …
[HTML][HTML] Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets
Non-human primate models will expedite therapeutics and vaccines for coronavirus disease
2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory …
2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory …
[HTML][HTML] A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations
The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets
M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …
[HTML][HTML] RIG-I-like receptor-mediated recognition of viral genomic RNA of severe acute respiratory syndrome coronavirus-2 and viral escape from the host innate …
T Kouwaki, T Nishimura, G Wang… - Frontiers in …, 2021 - frontiersin.org
RIG-I-like receptors (RLR), RIG-I and MDA5, are cytoplasmic viral RNA sensors that
recognize viral double-stranded RNAs and trigger signals to induce antiviral responses …
recognize viral double-stranded RNAs and trigger signals to induce antiviral responses …
[HTML][HTML] Immune cell dynamics deconvoluted by single-cell RNA sequencing in normothermic machine perfusion of the liver
Normothermic machine perfusion (NMP) has emerged as an innovative organ preservation
technique. Developing an understanding for the donor organ immune cell composition and …
technique. Developing an understanding for the donor organ immune cell composition and …