Nitric oxide and peroxynitrite in health and disease

P Pacher, JS Beckman, L Liaudet - Physiological reviews, 2007 - journals.physiology.org
The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Role of oxygen radicals in DNA damage and cancer incidence

M Valko, M Izakovic, M Mazur, CJ Rhodes… - Molecular and cellular …, 2004 - Springer
The development of cancer in humans and animals is a multistep process. The complex
series of cellular and molecular changes participating in cancer development are mediated …

ROS-induced hepatotoxicity under cypermethrin: involvement of the crosstalk between Nrf2/Keap1 and NF-κB/iκB-α pathways regulated by proteasome

H Zhao, Y Wang, Y Liu, K Yin, D Wang… - … science & technology, 2021 - ACS Publications
Cypermethrin (CMN) is a man-made insecticide, and its abuse has led to potential adverse
effects, particularly in sensitive populations such as aquatic organisms. The present study …

Effect of lipid peroxidation on membrane permeability of cancer and normal cells subjected to oxidative stress

J Van der Paal, EC Neyts, CCW Verlackt… - Chemical …, 2016 - pubs.rsc.org
We performed molecular dynamics simulations to investigate the effect of lipid peroxidation
products on the structural and dynamic properties of the cell membrane. Our simulations …

Molecular biomarkers of oxidative stress in aquatic organisms in relation to toxic environmental pollutants

A Valavanidis, T Vlahogianni, M Dassenakis… - Ecotoxicology and …, 2006 - Elsevier
The potential of oxygen free radicals and other reactive oxygen species (ROS) to damage
tissues and cellular components, called oxidative stress, in biological systems has become a …

Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress

C Michiels, M Raes, O Toussaint, J Remacle - Free radical Biology and …, 1994 - Elsevier
Eukaryotic cells have to constantly cope with highly reactive oxygen-derived free radicals.
Their defense against these free radicals is achieved by natural antioxidant molecules but …

Effect of lipid peroxidation on the properties of lipid bilayers: a molecular dynamics study

J Wong-Ekkabut, Z Xu, W Triampo, IM Tang… - Biophysical journal, 2007 - cell.com
Lipid peroxidation plays an important role in cell membrane damage. We investigated the
effect of lipid peroxidation on the properties of 1-palmitoyl-2-linoleoyl-sn-glycero-3 …

Mechanisms that regulate production of reactive oxygen species by cytochrome P450

RC Zangar, DR Davydov, S Verma - Toxicology and applied pharmacology, 2004 - Elsevier
Mammalian cytochromes P450 (P450) are a family of heme-thiolate enzymes involved in the
oxidative metabolism of a variety of endogenous and exogenous lipophilic compounds …

Metal–PAH mixtures in the aquatic environment: a review of co-toxic mechanisms leading to more-than-additive outcomes

PT Gauthier, WP Norwood, EE Prepas, GG Pyle - Aquatic toxicology, 2014 - Elsevier
Mixtures of metals and polycyclic aromatic hydrocarbons (PAHs) occur ubiquitously in
aquatic environments, yet relatively little is known regarding their combined toxicities …

Impact of oxidative stress on oocyte competence for in vitro embryo production programs

S Soto-Heras, MT Paramio - Research in Veterinary Science, 2020 - Elsevier
Producing high-competent oocytes during the in vitro maturation (IVM) is considered a key
step for the success of the in vitro production (IVP) of embryos. One of the known disruptors …