The dissolution behaviour and thermodynamic properties calculation of praziquantel in pure and mixed organic solvents

R Li, X Chen, G He, C Wu, Z Gan, Z He, J Zhao… - The Journal of Chemical …, 2020 - Elsevier
The purpose is to study the dissolution behaviour for praziquantel in different solvent. The
dissolution capacity within the temperature range from 273.15 K to 313.15 K was researched …

Solubility determination and thermodynamic properties calculation of macitentan in mixtures of ethyl acetate and alcohols

R Li, Y Jin, B Yu, Q Xu, X Chen, D Han - The Journal of Chemical …, 2021 - Elsevier
Due to macitentan (form I) is hydrophobic and has poor solubility, in this work, the solubility
of macitentan in (methanol+ ethyl acetate),(ethanol+ ethyl acetate) and (isopropanol+ ethyl …

Solid-liquid equilibrium and thermodynamic properties of dipyridamole form II in pure solvents and mixture of (N-methyl pyrrolidone+ isopropanol)

R Li, L Fu, J Zhang, W Wang, X Chen, J Zhao… - The Journal of Chemical …, 2020 - Elsevier
The solid–liquid equilibria of a poorly soluble drug namely dipyridamole were assayed to
determine solubility in pure and binary mixtures between 273.15 K and 313.15 K under …

Parametrization of PC-SAFT EoS for solvents reviewed for use in pharmaceutical process design: VLE, LLE, VLLE, and SLE study

J Yousefi Seyf, M Asgari - Industrial & Engineering Chemistry …, 2022 - ACS Publications
The perturbed chain-statistical associating fluid theory equation of state (PC-SAFT EoS) is
one of the state-of-the-art thermodynamic models used in the phase equilibrium calculation …

Solubility determination and thermodynamic characterization of orotic acid in twelve pure solvents and four binary mixed solvents

R Wang, C Chen, W Yang, P Zhou, F Zhu, H Xu… - Journal of Molecular …, 2021 - Elsevier
This research reports the solubility and thermodynamic characterization of orotic acid (OA)
when it reaches solid–liquid equilibrium in twelve pure solvents and four binary solvents …

The role of water-soluble polymers on the solubility of isophthalic acid in aqueous medium: Measurements, data correlation and thermodynamic analysis

M Barzegar-Jalali, P Jafari, S Hemmati, A Jouyban - Fluid Phase Equilibria, 2023 - Elsevier
The mole fraction solubility of isophthalic acid (IPA) was measured in water and four water-
soluble polymers including polyethylene glycol dimethyl ether 250 (PEGDME 250) and …

Determination of the solubility profile of isophthalic acid in some aqueous solutions of betaine-based deep eutectic solvents: Study the extent of H-bonding interactions …

P Jafari, M Barzegar-Jalali, S Hemmati… - … Chemistry and Pharmacy, 2023 - Elsevier
The equilibrium solubility of isophthalic acid (IPA) in three aqueous solutions of
betaine/propylene glycol (Bet/PG, 1: 5 M ratio), betaine/ethylene glycol (Bet/EG, 1: 3 M ratio) …

The solubility profile and apparent thermodynamic analysis of doxofylline in pure and mixed solvents

R Li, B Zhang, N Hou, C Li, J Xie, J He, X Chen… - The Journal of Chemical …, 2020 - Elsevier
Crystallization and purification is an important step in drug preparation. In this work, the
solubility of doxofylline in some pure and mixed solvents at T= 273.15–313.15 K was …

Solubility enhancement, solvent effect and thermodynamic analysis of pazopanib in co-solvent mixtures

H Shi, Y Xie, J Xu, J Zhu, C Wang, H Wang - The Journal of Chemical …, 2021 - Elsevier
As is known to all, co-solvency or solvent mixing is the most common and easy-to-use
method in the pharmaceutical industry for the improvement of solubility of poorly soluble …

The dissolution behavior and thermodynamic properties of amlodipine in mixtures of n-propanol/isopropanol+ water

Z Guoquan - The Journal of Chemical Thermodynamics, 2021 - Elsevier
Improving the solubility of poorly water-soluble drugs is one of the biggest problems. In this
study, the dissolution behavior of amlodipine in aqueous mixtures of co-solvents including n …