Invasive aspergillosis in critically ill patients: Review of definitions and diagnostic approaches

JD Jenks, HH Nam, M Hoenigl - Mycoses, 2021 - Wiley Online Library
Invasive aspergillosis (IA) is an increasingly recognised phenomenon in critically ill patients
in the intensive care unit, including in patients with severe influenza and severe coronavirus …

Aspergillus fumigatus and aspergillosis: From basics to clinics

A Arastehfar, A Carvalho, J Houbraken… - Studies in …, 2021 - ingentaconnect.com
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …

Performance of the Bronchoalveolar Lavage Fluid Aspergillus Galactomannan Lateral Flow Assay With Cube Reader for Diagnosis of Invasive Pulmonary …

JD Jenks, J Prattes, J Frank, B Spiess… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background The Aspergillus Galactomannan Lateral Flow Assay (LFA) is a rapid
test for the diagnosis of invasive aspergillosis (IA) that has been almost exclusively …

Salvage treatment for invasive aspergillosis and mucormycosis: challenges, recommendations and future considerations

M Egger, R Bellmann, R Krause, J Boyer… - Infection and drug …, 2023 - Taylor & Francis
Invasive mold diseases are devastating systemic infections which demand meticulous care
in selection, dosing, and therapy monitoring of antifungal drugs. Various circumstances …

An overview of using fungal DNA for the diagnosis of invasive mycoses

PL White, A Alanio, L Brown, M Cruciani… - Expert Review of …, 2022 - Taylor & Francis
Introduction Fungal PCR has undergone considerable standardization and, together with
the availability of commercial assays, external quality assessment schemes, and extensive …

Diagnosing pulmonary aspergillosis is much easier than it used to be: a new diagnostic landscape

DW Denning - The International Journal of Tuberculosis and …, 2021 - ingentaconnect.com
Significant innovations in the past decade have resulted in more sensitive and faster
diagnosis of allergic, chronic and invasive pulmonary aspergillosis, as well as Aspergillus …

Metagenomic Next-Generation Sequencing Assists in the Diagnosis of Mediastinal Aspergillus fumigatus Abscess in an Immunocompetent Patient: A Case Report …

W Deng, Y Jiang, J Qin, G Chen, Y Lv… - Infection and Drug …, 2023 - Taylor & Francis
Background Aspergillus fumigatus is an opportunistic fungal pathogen, which is commonly
found in lungs and rarely causes infections in mediastinum. Mediastinal Aspergillus abscess …

Superior Accuracy of Aspergillus Plasma Cell-Free DNA Polymerase Chain Reaction Over Serum Galactomannan for the Diagnosis of Invasive Aspergillosis

J Mah, V Nicholas, R Tayyar, A Moreno… - Clinical Infectious …, 2023 - academic.oup.com
Background Invasive aspergillosis (IA) in immunocompromised hosts carries high morbidity
and mortality. Diagnosis is often delayed because definitive diagnosis requires invasive …

Diagnosis of breakthrough fungal infections in the clinical mycology laboratory: an ECMM consensus statement

JD Jenks, JP Gangneux, IS Schwartz… - Journal of Fungi, 2020 - mdpi.com
Breakthrough invasive fungal infections (bIFI) cause significant morbidity and mortality. Their
diagnosis can be challenging due to reduced sensitivity to conventional culture techniques …

Invasive Pulmonary Aspergillosis Diagnosis via Peripheral Blood Metagenomic Next-Generation Sequencing

X Ma, S Zhang, H Xing, H Li, J Chen, H Li… - Frontiers in …, 2022 - frontiersin.org
Invasive pulmonary aspergillosis (IPA) is one of the major causes of morbidity and mortality
in immunocompromised patients such as hematological malignancies, hematopoietic stem …