[HTML][HTML] A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes

AM Dirir, M Daou, AF Yousef, LF Yousef - Phytochemistry Reviews, 2022 - Springer
Diabetes mellitus is a multifactorial global health disorder that is rising at an alarming rate.
Cardiovascular diseases, kidney damage and neuropathy are the main cause of high …

[HTML][HTML] Natural products inhibitors of monoamine oxidases—Potential new drug leads for neuroprotection, neurological disorders, and neuroblastoma

ND Chaurasiya, F Leon, I Muhammad, BL Tekwani - Molecules, 2022 - mdpi.com
Monoamine oxidase inhibitors (MAOIs) are an important class of drugs prescribed for
treatment of depression and other neurological disorders. Evidence has suggested that …

[HTML][HTML] Phytochemistry, Ethnopharmacological Uses, Biological Activities, and Therapeutic Applications of Cassia obtusifolia L.: A Comprehensive Review

MY Ali, S Park, M Chang - Molecules, 2021 - mdpi.com
Cassia obtusifolia L., of the Leguminosae family, is used as a diuretic, laxative, tonic,
purgative, and natural remedy for treating headache, dizziness, constipation, tophobia, and …

[HTML][HTML] Reveals of new candidate active components in hemerocallis radix and its anti-depression action of mechanism based on network pharmacology approach

HY Lin, JC Tsai, LY Wu, WH Peng - International journal of molecular …, 2020 - mdpi.com
The global depression population is showing a significant increase. Hemerocallis fulva L. is
a common Traditional Chinese Medicine (TCM). Its flower buds are known to have ability to …

Luteolin, a Potent Human Monoamine Oxidase-A Inhibitor and Dopamine D4 and Vasopressin V1A Receptor Antagonist

SE Park, P Paudel, A Wagle, SH Seong… - Journal of Agricultural …, 2020 - ACS Publications
Luteolin, a flavonoid widely distributed in the plant kingdom, contains two benzene rings and
hydroxyl groups, and this structural specificity contributes to its diverse biological activities …

In vitro and in vivo exploration of the anti-atopic dermatitis mechanism of action of Tibetan medicine Qi-Sai-Er-Sang-Dang-Song decoction

J Liu, Y Tao, X Zou, Q Liu, X Meng, Y Zhang… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Tibetan medicine Qi-Sai-Er-Sang-Dang-Song
Decoction (QSD, ཆུ་ སེར་ སེང་ ལྡེང་ སུམ་ ཐང་།) is a traditional Tibetan medical …

[HTML][HTML] Novel Diels–Alder Type Adducts from Morus alba Root Bark Targeting Human Monoamine Oxidase and Dopaminergic Receptors for the Management of …

P Paudel, SE Park, SH Seong, HA Jung… - International Journal of …, 2019 - mdpi.com
In this study, we delineate the human monoamine oxidase (h MAO) inhibitory potential of
natural Diels–Alder type adducts, mulberrofuran G (1), kuwanon G (2), and albanol B (3) …

Rational redesign of monoamine oxidase A into a dehydrogenase to probe ROS in cardiac aging

LG Iacovino, N Manzella, J Resta… - ACS Chemical …, 2020 - ACS Publications
Cardiac senescence is a typical chronic frailty condition in the elderly population, and
cellular aging is often associated with oxidative stress. The mitochondrial-membrane …

Bromophenols from Symphyocladia latiuscula Target Human Monoamine Oxidase and Dopaminergic Receptors for the Management of Neurodegenerative …

P Paudel, SE Park, SH Seong, HA Jung… - Journal of agricultural …, 2020 - ACS Publications
Progressive degeneration of dopaminergic neurons in the substantia nigra is the
characteristic feature of Parkinson's disease (PD) and the severity accelerates with aging …

Rh(III)-Catalyzed Synthesis of Amino-isocoumarins with N-Functionalized Cyclic Carbonates via C–H/O–H Annulation

Y Zhang, H Wang, J Bai, Q Liu, J Cui, Y Huang - Organic Letters, 2022 - ACS Publications
A practical method to access amino-isocoumarins catalyzed by a Rh (III) complex through
redox-neutral C–H/O–H annulation has been disclosed. The use of N-functionalized cyclic …