[HTML][HTML] When Bacteria and Viruses Collide: A Tale of Chlamydia trachomatis and Sexually Transmitted Viruses

E Ghasemian, E Harding-Esch, D Mabey, MJ Holland - Viruses, 2023 - mdpi.com
The global incidence of sexually transmitted infections (STIs) remains high, with the World
Health Organization (WHO) estimating that over 1 million people acquire STIs daily. STIs …

[HTML][HTML] Efficacy of Pgp3 vaccination for Chlamydia urogenital tract infection depends on its native conformation

B Peng, S Zhong, Y Hua, Q Luo, W Dong… - Frontiers in …, 2022 - frontiersin.org
Urogenital tract infections with Chlamydia trachomatis have frequently been detected among
patients diagnosed with sexually transmitted infections, and such infections lead to …

[HTML][HTML] Overexpression of the Bam Complex Improves the Production of Chlamydia trachomatis MOMP in the E. coli Outer Membrane

DT Huynh, WSP Jong, GM Koningstein… - International Journal of …, 2022 - mdpi.com
A licensed Chlamydia trachomatis (Ct) vaccine is not yet available. Recombinant Chlamydia
trachomatis major outer membrane protein (Ct-MOMP), the most abundant constituent of the …

[HTML][HTML] Sensitive and visual identification of Chlamydia trachomatis using multiple cross displacement amplification integrated with a gold nanoparticle-based lateral …

X Chen, W Yuan, Q Zhou, Y Tan, R Wang… - Frontiers in Cellular and …, 2022 - frontiersin.org
Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infection (STI)
and remains a major public health challenge, especially in less-developed regions …

[HTML][HTML] Evaluation of three formulations based on Polymorphic membrane protein D in mice infected with Chlamydia trachomatis

RC Russi, D Del Balzo, IG Reidel… - Frontiers in …, 2023 - frontiersin.org
The significant impact of Chlamydia trachomatis (Ct) infections worldwide highlights the
need to develop a prophylactic vaccine that elicits effective immunity and protects the host …

[HTML][HTML] Molecular pathogenesis of Chlamydia trachomatis

B Jury, C Fleming, WM Huston… - Frontiers in Cellular and …, 2023 - ncbi.nlm.nih.gov
Chlamydia trachomatis is a strict intracellular human pathogen. It is the main bacterial cause
of sexually transmitted infections and the etiologic agent of trachoma, which is the leading …

A novel chimeric recombinant FliC-Pgp3 vaccine promotes immunoprotection against Chlamydia muridarum infection in mice

L Zhao, X Wang, Z Li - International Journal of Biological Macromolecules, 2024 - Elsevier
The Pgp3 subunit vaccine elicits immune protection against Chlamydia trachomatis
infection, but additional adjuvants are still required to enhance its immunoprotective efficacy …

Intranasal delivery of Salmonella OMVs decorated with Chlamydia trachomatis antigens induces specific local and systemic immune responses

DT Huynh, E Nolfi, L Medfai, P van Ulsen… - Human Vaccines & …, 2024 - Taylor & Francis
Chlamydia trachomatis is an obligate intracellular pathogen responsible for the most
prevalent bacterial sexually transmitted disease globally. The high prevalence of chlamydial …

[PDF][PDF] Designing a multi-epitope vaccine against Chlamydia trachomatis by employing integrated core proteomics, immuno-informatics and in silico approaches …

S Aslam, S Ahmad, F Noor, UA Ashfaq, F Shahid… - 2023 - academia.edu
Chlamydia trachomatis, a Gram-negative bacterium that infects the rectum, urethra,
congenital sites, and columnar epithelium of the cervix. It is a major cause of preventable …

Efficacy of a novel affitoxin targeting MOMP against Chlamydia trachomatis in vitro and in vivo

M Li, J Yang, L Zhou, J Zhang, Y Li… - The Journal of …, 2024 - academic.oup.com
Targeted therapy is an attractive approach for treating infectious diseases. Affibody
molecules have similar capability to antibodies that facilitate molecular recognition in both …