High-throughput immunoglobulin sequencing promises new insights into the somatic
hypermutation and antigen-driven selection processes that underlie B-cell affinity maturation …

In the human, most IgM+ IgD+ as well as CD5* peripheral blood B cells express unmutated
V genes and thus can be assigned to a pre‐germinal centre (GC) stage of development. The …

To clarify the relationships between marginal zone lymphomas (MZLs) and Waldenström
macroglobulinemia/lymphoplasmacytic lymphomas (WM/LPLs), immunoglobulin heavy …

The BCL6 gene encodes a zinc-finger transcription factor and is altered by chromosomal
arrangements in its 5'noncoding region in approximately 30% of diffuse large-cell lymphoma …

The diversity of the human antibody repertoire that is generated by V (D) J gene
rearrangement is extended by nine constant region genes that give antibodies their complex …

The accumulation of B lymphocyte clones in the cerebrospinal fluid (CSF) of patients with
multiple sclerosis (MS) and patients with other neurological disorders was investigated …

The splenic marginal zone (MGZ), which surrounds the mantle zone (MTZ) in human splenic
white pulp, contains a phenotypically and morphologically distinct population of B cells. The …

A high prevalence of chronic hepatitis C virus (HCV) infection has recently been shown in a
subset of B-cell non-Hodgkin's lymphomas, most of which belong to the lymphoplasmacytoid …

Kawasaki Disease (KD) is a potentially fatal acute vasculitis of childhood. Although KD is the
leading cause of acquired heart disease in children in developed nations, its pathogenesis …

Chronic lymphocytic leukemia (CLL) is a B-cell tumor involving small lymphocytes that
generally express the CD5 antigen and low levels of surface Ig. Within this definition, there is …