Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Ruminococcus gnavus was first identified in 1974 as a strict anaerobe in the gut of healthy
individuals, and for several decades, its study has been limited to specific enzymes or …

It is currently well established that multicellular organisms live in tight association with
complex communities of microorganisms including a large number of bacteria. These are …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are of
increasing interest in natural products as well as drug discovery. This empowers not only the …

Propionate is an important platform chemical that is available through petrochemical
synthesis. Bacterial propionate formation is considered an alternative, as bacteria can …

Antibiotics are essential weapons in our fight against infectious disease, yet the
consequences of broad-spectrum antibiotic use on microbiome stability and pathogen …

Cystic fibrosis (CF) is associated with repeated lung bacterial infection, mainly by
Pseudomonas aeruginosa, Staphylococcus aureus, and Mycobacterium abscessus, all …

In a scenario where the discovery of new molecules to fight antibiotic resistance is a public
health concern, ribosomally synthesized and post-translationally modified peptides …

The accelerating discovery of structurally distinct peptide natural products bearing α-
thioether cross-links, such as the family of sactipeptide natural products, highlights the need …

Microbial communities from various environments have been studied in the quest for new
natural products with a broad range of applications in medicine and biotechnology. We …