Ocular graft-versus-host-disease (GVHD) remains a significant clinical complication after
allogeneic hematopoietic stem cell transplantation. Impaired visual function, pain, and other …

One of the most remarkable advancements in medical treatments of corneal diseases in
recent decades has been corneal transplantation. However, corneal transplants, including …

Fungal keratitis (FK) is a serious, potentially sight-threatening corneal infection, which is
associated with poor prognosis. A20, also called TNFAIP3, plays significant roles in the …

Graft-versus-host disease (GVHD) is a complex immune-mediated condition that arises
when donor T-cells recognize recipient antigens as foreign, which culminates to a …

Corneal blindness affects greater than 5 million individuals, with over 180,000 corneal
transplantations (CTs) performed annually. Inhigh-risk CTs, almost all grafts are rejected …

Glaucoma and uveitis are non-vascular ocular diseases which are among the leading
causes of blindness and visual loss. These conditions have distinct characteristics and …

This review, which is part of the “Currents in One Health” series, describes the importance of
the study of immune-mediated ocular disease in the development of innovative therapeutics …

Hydrogels are 3D networks swollen with water. They are biocompatible, strong, and
moldable and are emerging as a promising biomedical material for regenerative medicine …

Adeno-associated viral transduction allows the introduction of nucleic fragments into cells
and is widely used to modulate gene expressions in vitro and in vivo. It enables the study of …

Research in cancer drug development has witnessed a rapid evolution over the past
decades, which aims to develop active biological interventions and control cancer-promising …