The five genes of the lysyl oxidase family encode enzymes that covalently cross-link
components of the extracellular matrix, such as various types of collagen and elastin, and …

Simple Summary In the field of non-small cell lung cancer (NSCLC), there have been
significant advancements in genomic data and bioinformatics tools, which have improved …

The adenosine pathway is an exciting new target in the field of cancer immunotherapy.
CD73 is the main producer of extracellular adenosine. Non-small cell lung cancer (NSCLC) …

Snail is implicated in tumour growth and metastasis and is up-regulated in various human
tumours. Although the role of Snails in epithelial-mesenchymal transition, which is …

Introduction: Lung adenocarcinoma (LUAD) is the most prevalent pathological subtype of
non-small cell lung cancer (NSCLC), characterized by a high propensity for relapse and …

Epithelial-mesenchymal transition (EMT) is crucial to metastasis by increasing cancer cell
migration and invasion. At the cellular level, EMT-related morphological and functional …

Lung cancer frequently affects patients with Chronic Obstructive Pulmonary Disease
(COPD). Cigarette smoke (CS) fosters cancer progression by increasing oxidative stress and …

Background The expression of programmed death-ligand 1 (PD-L1), tumor-infiltrating
lymphocytes (TILs), E-cadherin, and vimentin in lung cancer tumor microenvironment is …

Epithelial-to-mesenchymal transition (EMT) is a reversible process, in which epithelial cells
lose their epithelial traits and acquire a mesenchymal phenotype. This transformation has …

Advanced or metastatic breast cancer affects multiple organs and is a leading cause of
cancer-related death. Cancer metastasis is associated with epithelial-mesenchymal …