Background Numerous studies have reported that the amnestic-type mild cognitive
impairment (aMCI) patients have impaired brain structural integrity and functional alterations …

OBJECTIVE: To identify predictors of the progression from pre-dementia stages of cognitive
impairment in Alzheimer's disease is relevant to clinical management and to substantiate the …

Background Altered hippocampal structure and function is a valuable indicator of possible
conversion from amnestic type mild cognitive impairment (aMCI) to Alzheimer's disease …

OBJECTIVE: Alzheimer's disease (AD) and frontotemporal dementia (FTD) are among the
most frequent neurodegenerative cognitive disorders, but their differential diagnosis is …

Accurate classification of either patients with Alzheimer's disease (AD) or patients with mild
cognitive impairment (MCI), the prodromal stage of AD, from cognitively unimpaired (CU) …

Understanding the contribution of cerebrovascular factors in the progression of cognitive
decline in Alzheimer's disease (AD) is a key step for the development of preventive …

This study aimed to identify preclinical Alzheimer's disease (AD) in patients with mild
cognitive impairment (MCI) using measurements of both regional cerebral blood flow (rCBF) …

Mild cognitive impairment (MCI) is a heterogeneous condition associated with increased risk
of Alzheimer's disease (AD) and other dementias. This study aimed to identify areas of initial …

Recent brain imaging studies have found changes in subcortical regions in presymptomatic
autosomal dominant Alzheimer's disease (ADAD). These regions are also affected in …

This review examines new biomolecular findings that lend support to the hemodynamic role
played by chronic brain hypoperfusion (CBH) in driving a pathway to Alzheimer's disease …