Molecular mechanisms of neuroplasticity: an expanding universe

NV Gulyaeva - Biochemistry (Moscow), 2017 - Springer
Biochemical processes in synapses and other neuronal compartments underlie
neuroplasticity (functional and structural alterations in the brain enabling adaptation to the …

[HTML][HTML] Intermittent hypoxic training as an effective tool for increasing the adaptive potential, endurance and working capacity of the brain

EA Rybnikova, NN Nalivaeva, MY Zenko… - Frontiers in …, 2022 - frontiersin.org
This review is devoted to the phenomenon of intermittent hypoxic training and is aimed at
drawing the attention of researchers to the necessity of studying the mechanisms mediating …

Hypoxic conditioning and the central nervous system: A new therapeutic opportunity for brain and spinal cord injuries?

S Baillieul, S Chacaroun, S Doutreleau… - Experimental …, 2017 - journals.sagepub.com
Central nervous system diseases are among the most disabling in the world.
Neuroprotection and brain recovery from either acute or chronic neurodegeneration still …

[HTML][HTML] Remote ischemic postconditioning vs. physical exercise after stroke: an alternative rehabilitation strategy?

X Geng, Q Wang, H Lee, C Huber, M Wills, K Elkin… - Molecular …, 2021 - Springer
There remain debates on neuroprotection and rehabilitation techniques for acute ischemic
stroke patients. Therapeutic physical exercise following stroke has shown promise but is …

[HTML][HTML] Neuroglobin mediates neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in rats through preserving the activity of Na+/K+ …

H Wen, L Liu, L Zhan, D Liang, L Li, D Liu, W Sun… - Cell death & …, 2018 - nature.com
Hypoxic postconditioning (HPC) is an innovative neuroprotective strategy with cytoprotective
effects on the hippocampal neurons against transient global cerebral ischemia (tGCI) in …

[HTML][HTML] DJ-1: A promising therapeutic candidate for ischemia-reperfusion injury

F De Lazzari, HA Prag, AV Gruszczyk, AJ Whitworth… - Redox Biology, 2021 - Elsevier
DJ-1 is a multifaceted protein with pleiotropic functions that has been implicated in multiple
diseases, ranging from neurodegeneration to cancer and ischemia-reperfusion injury …

[HTML][HTML] Intermittent hypoxia training prevents deficient learning-memory behavior in mice modeling Alzheimer's disease: a pilot study

MG Ryou, X Chen, M Cai, H Wang, ME Jung… - Frontiers in aging …, 2021 - frontiersin.org
In mouse models of Alzheimer's disease (AD), normobaric intermittent hypoxia training (IHT)
can preserve neurobehavioral function when applied before deficits develop, but IHT's …

Pharmacological HIF1 inhibition eliminates downregulation of the pentose phosphate pathway and prevents neuronal apoptosis in rat hippocampus caused by severe …

O Vetrovoy, K Sarieva, E Lomert, P Nimiritsky… - Journal of Molecular …, 2020 - Springer
The pentose phosphate pathway (PPP) of glucose metabolism in the brain serves as a
primary source of NADPH which in turn plays a crucial role in multiple cellular processes …

Neuroprotective mechanism of hypoxic post-conditioning involves HIF1-associated regulation of the pentose phosphate pathway in rat brain

O Vetrovoy, K Sarieva, O Galkina, N Eschenko… - Neurochemical …, 2019 - Springer
Post-conditioning is exposure of an injured organism to the same harmful factors but of
milder intensity which mobilizes endogenous protective mechanisms. Recently, we have …

[HTML][HTML] Disrupted autonomic pathways in spinal cord injury: Implications for the immune regulation

MM Moura, A Monteiro, AJ Salgado, NA Silva… - Neurobiology of …, 2024 - Elsevier
Abstract Spinal Cord Injury (SCI) disrupts critical autonomic pathways responsible for the
regulation of the immune function. Consequently, individuals with SCI often exhibit a …