Single-cell genomic technologies are revealing the cellular composition, identities and
states in tissues at unprecedented resolution. They have now scaled to the point that it is …

Single cell genomics encompasses a suite of rapidly maturing technologies that measure
the molecular profiles of individual cells within target samples. These approaches provide a …

Pathway analysis is a key analytical stage in the interpretation of omics data, providing a
powerful method for detecting alterations in cellular processes. We recently developed a …

Non-melanoma skin cancers (NMSCs) are the fifth most common type of cancer worldwide,
affecting both men and women. Each year, more than a million new occurrences of NMSC …

Hundreds of millions of single cells have been analyzed to date using high throughput
transcriptomic methods, thanks to technological advances driving the increasingly rapid …

Altered glycoprotein expression is an undisputed corollary of cancer development.
Understanding these alterations is paramount but hampered by limitations underlying …

Background Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of
transcriptomes, arising as a powerful tool for discovering and characterizing cell types and …

The dog is valued as a companion animal and increasingly recognized as a model for
human disorders. Given the importance of T cells in health and disease, comprehensive …

Pet dogs develop spontaneous cancers at a rate estimated to be five times higher than that
of humans, providing a unique opportunity to study disease biology and evaluate novel …

The transcriptomic profile of a cell population can now be studied at the cellular level using
single-cell mRNA sequencing (scRNA-seq). This novel technique provides the …