[HTML][HTML] Sunitinib resistance in renal cell carcinoma: From molecular mechanisms to predictive biomarkers
Currently, renal cell carcinoma (RCC) is the most prevalent type of kidney cancer. Targeted
therapy has replaced radiation therapy and chemotherapy as the main treatment option for …
therapy has replaced radiation therapy and chemotherapy as the main treatment option for …
Long non-coding RNAs in cancer: implications for diagnosis, prognosis, and therapy
Y Qian, L Shi, Z Luo - Frontiers in medicine, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are major components of cellular transcripts that are
arising as important players in various biological pathways. They have received extensive …
arising as important players in various biological pathways. They have received extensive …
Small molecule recognition of disease-relevant RNA structures
SM Meyer, CC Williams, Y Akahori, T Tanaka… - Chemical Society …, 2020 - pubs.rsc.org
Targeting RNAs with small molecules represents a new frontier in drug discovery and
development. The rich structural diversity of folded RNAs offers a nearly unlimited reservoir …
development. The rich structural diversity of folded RNAs offers a nearly unlimited reservoir …
[HTML][HTML] Exploring the mechanisms behind long noncoding RNAs and cancer
MM Balas, AM Johnson - Non-coding RNA research, 2018 - Elsevier
Over the past decade, long noncoding RNAs (lncRNAs) have been identified as significant
players in gene regulation. They are often differentially expressed and widely-associated …
players in gene regulation. They are often differentially expressed and widely-associated …
HOTAIR: a potential metastatic, drug-resistant and prognostic regulator of breast cancer
HOX transcript antisense intergenic RNA (HOTAIR) is an oncogenic non-coding RNA whose
expression is strongly correlated with the tumor grade and prognosis of a variety of …
expression is strongly correlated with the tumor grade and prognosis of a variety of …
LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer
A Bhan, SS Mandal - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2015 - Elsevier
Non-coding RNAs (ncRNAs) are emerging classes of regulatory RNA that play key roles in
various cellular and physiological processes such as in gene regulation, chromatin …
various cellular and physiological processes such as in gene regulation, chromatin …
Long non‐coding RNAs in development and disease: conservation to mechanisms
I Tsagakis, K Douka, I Birds… - The Journal of …, 2020 - Wiley Online Library
Our genomes contain the blueprint of what makes us human and many indications as to why
we develop disease. Until the last 10 years, most studies had focussed on protein‐coding …
we develop disease. Until the last 10 years, most studies had focussed on protein‐coding …
Lnc2Cancer: a manually curated database of experimentally supported lncRNAs associated with various human cancers
Abstract Lnc2Cancer (http://www. bio-bigdata. net/lnc2cancer) is a manually curated
database of cancer-associated long non-coding RNAs (lncRNAs) with experimental support …
database of cancer-associated long non-coding RNAs (lncRNAs) with experimental support …
HOTAIR LncRNA: a novel oncogenic propellant in human cancer
T Rajagopal, S Talluri, RL Akshaya, NR Dunna - Clinica chimica acta, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) are an important novel class of non-coding RNAs having
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …
Expression of the long non-coding RNA HOTAIR correlates with disease progression in bladder cancer and is contained in bladder cancer patient urinary exosomes
Exosomes are 30-150nM membrane-bound secreted vesicles that are readily isolated from
biological fluids such as urine (UEs). Exosomes contain proteins, micro RNA (miRNA) …
biological fluids such as urine (UEs). Exosomes contain proteins, micro RNA (miRNA) …