Monocyte biology conserved across species: Functional insights from cattle

SC Talker, GT Barut, HEL Lischer, R Rufener… - Frontiers in …, 2022 - frontiersin.org
Similar to human monocytes, bovine monocytes can be split into CD14highCD16-classical,
CD14highCD16high intermediate and CD14-/dimCD16high nonclassical monocytes (cM …

Chemerin promotes the pathogenesis of preeclampsia by activating CMKLR1/p-Akt/CEBPɑ axis and inducing M1 macrophage polarization

ZS Ji, H Jiang, Y Xie, QP Wei, XF Yin, JH Ye… - Cell biology and …, 2022 - Springer
A higher ratio of M1/M2 macrophages and an elevated chemerin level are both related to
increased risk of preeclampsia. However, the crosstalk between these two events and their …

Biomarkers of haemodynamic severity of systemic sclerosis-associated pulmonary arterial hypertension by serum proteome analysis

S Sanges, L Rice, L Tu, E Valenzi… - Annals of the …, 2023 - ard.bmj.com
Objectives To mine the serum proteome of patients with systemic sclerosis-associated
pulmonary arterial hypertension (SSc-PAH) and to detect biomarkers that may assist in …

Understanding the role of chemerin in the pathophysiology of pre-eclampsia

K Pankiewicz, T Issat - Antioxidants, 2023 - mdpi.com
Chemerin is a multifaceted adipokine that is involved in multiple biological processes,
including inflammation, angiogenesis, adipogenesis, and energy metabolism, as well as …

Neutrophils regulate tumor angiogenesis in oral squamous cell carcinoma and the role of Chemerin

F Gao, Y Feng, X Hu, X Zhang, T Li, Y Wang… - International …, 2023 - Elsevier
Oral squamous cell carcinoma (OSCC) is the most common malignant tumor of the oral
cavity. Tumor angiogenesis plays a crucial role in tumor progression. Studies have …

HOXA9-induced chemerin signals through CMKLR1/AMPK/TXNIP/NLRP3 pathway to induce pyroptosis of trophoblasts and aggravate preeclampsia

XZ Quan, JH Ye, XZ Yang, Y Xie - Experimental Cell Research, 2021 - Elsevier
Background Up-regulated chemerin correlates with the risk and the severity of
preeclampsia. In this study, we examined impacts and underlying mechanisms by which …

Chemerin in atherosclerosis

JX Sun, C Zhang, ZB Cheng, MY Tang, YZ Liu… - Clinica Chimica …, 2021 - Elsevier
Atherosclerosis (AS), a chronic arterial disease, is characterized by endothelial dysfunction,
inflammatory reactions and lipid accumulation in parallel with aberrant angiogenesis and …

Serum chemerin concentration is associated with proinflammatory status in chronic coronary syndrome

A Szpakowicz, M Szpakowicz, M Lapinska, M Paniczko… - Biomolecules, 2021 - mdpi.com
Background: Chemerin is an adipokine and a chemoattractant for leukocytes. Increased
chemerin levels were observed in patients with coronary artery disease (CAD). We …

Anti-tumoral effect of chemerin on ovarian cancer cell lines mediated by activation of interferon alpha response

M Schmitt, J Gallistl, S Schüler-Toprak, J Fritsch… - Cancers, 2022 - mdpi.com
Simple Summary Chemerin is a multifunctional protein with an important role in the immune
system. Recent evidence showed that chemerin also regulates the development of cancer …

[HTML][HTML] Single-Cell Transcriptomics Reveals Cellular Heterogeneity and Complex Cell–Cell Communication Networks in the Mouse Cornea

YF Wu, NW Chang, LA Chu, HY Liu… - … & Visual Science, 2023 - tvst.arvojournals.org
Purpose: To generate a single-cell RNA-sequencing (scRNA-seq) map and construct cell–
cell communication networks of mouse corneas. Methods: C57BL/6 mouse corneas were …