[HTML][HTML] Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems

DA Subramanian, R Langer, G Traverso - Journal of Nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …

[HTML][HTML] Tailoring functional nanoparticles for oral vaccine delivery: Recent advances and future perspectives

P Cao, ZP Xu, L Li - Composites Part B: Engineering, 2022 - Elsevier
The oral vaccine has attracted much interest due to easy administration, induction of local
and systemic immune responses, and pain relief. Nowadays, functional nanoparticles and …

[HTML][HTML] Silica nanoparticles in transmucosal drug delivery

TM M. Ways, KW Ng, WM Lau, VV Khutoryanskiy - Pharmaceutics, 2020 - mdpi.com
Transmucosal drug delivery includes the administration of drugs via various mucous
membranes, such as gastrointestinal, nasal, ocular, and vaginal mucosa. The use of …

[HTML][HTML] Influence of chemical and bio-surfactants on physiochemical properties in mesoporous silica nanoparticles synthesis

RK Sharma, G Dey, P Banerjee, JP Maity, CM Lu… - Journal of Materials …, 2023 - Elsevier
The present study pointedly investigates the synthesis of mesoporous silica nanoparticles
(sol–gel method) using four different surfactants (biosurfactants, CTAB, SDS and tween-80) …

[HTML][HTML] The design of anionic surfactant-based amino-functionalized mesoporous silica nanoparticles and their application in transdermal drug delivery

A Almomen, AM El-Toni, M Badran, A Alhowyan… - Pharmaceutics, 2020 - mdpi.com
Melanoma remains the most lethal form of skin cancer and most challenging to treat despite
advances in the oncology field. Our work describes the utilization of nanotechnology to …

[HTML][HTML] From synthetic route of silica nanoparticles to theranostic applications

P Pallavi, K Harini, S Alshehri, MM Ghoneim… - Processes, 2022 - mdpi.com
The advancements in nanotechnology have quickly developed a new subject with vast
applications of nanostructured materials in medicine and pharmaceuticals. The enormous …

Aptamer-modified chitosan-capped mesoporous silica nanoparticles for co-delivery of cytarabine and daunorubicin in leukemia

SR Heydari, MH Ghahremani, F Atyabi… - International Journal of …, 2023 - Elsevier
In this study, surface modified mesoporous silica nanoparticles (MSNs) were prepared for
the targeted delivery of the anticancer agents, daunorubicin (DNR) and cytarabine (CTR) …

Mucoadhesive vaccine delivery systems for the oral mucosa

K Mokabari, M Iriti, EM Varoni - Journal of Dental Research, 2023 - journals.sagepub.com
Vaccine technology has evolved continuously since its beginning, and mucosal vaccination,
including intranasal, sublingual, and oral administrations, has recently gained great …

Innovative vaccine platforms against infectious diseases: Under the scope of the COVID-19 pandemic

M Tsakiri, N Naziris, C Demetzos - International Journal of Pharmaceutics, 2021 - Elsevier
While classic vaccines have proved greatly efficacious in eliminating serious infectious
diseases, innovative vaccine platforms open a new pathway to overcome dangerous …

tert-Butylamine functionalized MCM-41 mesoporous nanoparticles as drug carriers for the controlled release of cyclophosphamide anticancer drug

Z Shariatinia, N Pourzadi, SMR Darvishi - Surfaces and Interfaces, 2021 - Elsevier
Mesoporous MCM-41 nanoparticles were synthesized and functionalized using 13-21% of
tert-butylamine (TBA) and applied as efficient drug delivery systems (DDSs). The anticancer …