Dynamical modelling of haematopoiesis: an integrated view over the system in homeostasis and under perturbation

E Manesso, J Teles, D Bryder… - Journal of the Royal …, 2013 - royalsocietypublishing.org
A very high number of different types of blood cells must be generated daily through a
process called haematopoiesis in order to meet the physiological requirements of the …

A continuous model of three scenarios of the infection process with delayed immune response factors

AY Perevaryukha - Biophysics, 2021 - Springer
The course of an infection was modeled as a controlled nonlinear process. Understanding
the substantial differences observed in the trajectory of the disease caused by the new …

Gnotobiotic mouse model's contribution to understanding host–pathogen interactions

K Kubelkova, M Benuchova, H Kozakova… - Cellular and molecular …, 2016 - Springer
This brief review is dedicated to the legacy of Prof. Jaroslav Šterzl and his colleagues, who
laid the foundation for gnotobiology in the former Czechoslovakia 55 years. Prof. Sterzl …

Computational modelling and simulation of the immune system

JK Kalita, K Chandrashekar, R Hans… - International …, 2006 - inderscienceonline.com
We have developed a software system called SIMISYS that models and simulates aspects of
the human immune system based on the computational framework of cellular automata. We …

Непрерывная модель трех сценариев инфекционного процесса при факторах запаздывания иммунного ответа

АЮ Переварюха - Биофизика, 2021 - elibrary.ru
Рассмотрены модели развития инфекции как регулируемые нелинейные процессы.
Актуальным вопросом для анализа оказались существенные различия в динамике …

The use of gnotobiological models for the studies of immune mechanisms

J Šterzl, L Mandel, R Štêánková - Food/Nahrung, 1987 - Wiley Online Library
Germfree (GF) animals are widely used for discrimination of natural mechanisms
(genetically determined) from adaptive mechanisms of immunity induced by external …

Mathematical model of B lymphocyte replacement kinetics: its application to the recovery from tolerance in adult mice

P Klein, T Hraba, J Doležal - Mathematical biosciences, 1985 - Elsevier
In a previous paper a simple mathematical model was developed, describing the induction
of B cell tolerance by direct inactivation of immunocompetent cells by antigen, and the …

[PDF][PDF] A model of proliferation control in immune response

D Přikrylová, M Jílek, J Doležal - Kybernetika, 1984 - dml.cz
A considerable proliferation of participating cells is a characteristic feature of the immune
response. Some new experimental findings suggest that this proliferation is controlled by a …

Lymphocyte differentiation, repertoire development and migration: The need for mathematical models

JR Lumb - Computers & Mathematics with Applications, 1987 - Elsevier
The immune system is a tremendously complicated and important system, whose central
players, the lymphocytes, are able to recognize specific foreign invaders (antigens) with their …

A review of quantitative modeling of B cell responses to antigenic challenge

TP Hickling, X Chen, P Vicini, S Nayak - Journal of pharmacokinetics and …, 2014 - Springer
A key role of B cells in the mammalian immune response is the generation of antibodies that
serve to protect the organism against antigenic challenges. The same process may also be …