[HTML][HTML] Advanced applications of cellulose-based composites in fighting bone diseases

J Deng, Q Song, S Liu, W Pei, P Wang, L Zheng… - Composites Part B …, 2022 - Elsevier
Bone diseases, such as bone defects, cartilage damage, osteomyelitis, and osteoporosis,
are a primary focus area in current research. Cellulose and its derivatives, the most …

Osteoporosis therapies and their mechanisms of action

B Kim, YJ Cho, W Lim - Experimental and therapeutic …, 2021 - spandidos-publications.com
Osteoporosis is a common disease that affects millions of patients worldwide and is most
common in menopausal women. The main characteristics of osteoporosis are low bone …

Structural characterization and anti-osteoporosis effects of polysaccharide purified from Eucommia ulmoides Oliver cortex based on its modulation on bone …

J Song, Y Zhang, Y Zhu, X Jin, L Li, C Wang… - Carbohydrate …, 2023 - Elsevier
EuOCP3, with a molecular weight of 38.1 kDa, is an acidic polysaccharide purified from
Eucommia ulmoides Oliver cortex. Herein, we determined that the main backbone of …

Osteoporosis remission and new bone formation with mesoporous silica nanoparticles

P Mora‐Raimundo, D Lozano, M Benito… - Advanced …, 2021 - Wiley Online Library
Nanotechnology changed the concept of treatment for a variety of diseases, producing a
huge impact regarding drug and gene delivery. Among the different targeted diseases …

Recent progresses in the treatment of osteoporosis

SS Li, SH He, PY Xie, W Li, XX Zhang, TF Li… - Frontiers in …, 2021 - frontiersin.org
Osteoporosis (OP) is a chronic bone disease characterized by aberrant microstructure and
macrostructure of bone, leading to reduced bone mass and increased risk of fragile …

Near-infrared light-controlled and real-time detection of osteogenic differentiation in mesenchymal stem cells by upconversion nanoparticles for osteoporosis therapy

R Yan, Y Guo, X Wang, G Liang, A Yang, J Li - ACS nano, 2022 - ACS Publications
Osteoporosis (OP) is one of the most common diseases in the elderly, and it is not effectively
solved by current treatments. Mesenchymal stem cells (MSCs) have multiple differentiation …

[HTML][HTML] Osteoporosis and fragility fractures: currently available pharmacological options and future directions

HP Dimai, A Fahrleitner-Pammer - Best practice & research Clinical …, 2022 - Elsevier
Osteoporosis is a systemic skeletal disease characterized by low bone mass and
microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility …

[HTML][HTML] Pharmaceutical treatment of bone loss: From animal models and drug development to future treatment strategies

MB Brent - Pharmacology & Therapeutics, 2023 - Elsevier
Animal models are fundamental to advance our knowledge of the underlying
pathophysiology of bone loss and to study pharmaceutical countermeasures against it. The …

Bone‐targeted delivery of cell‐penetrating‐RUNX2 fusion protein in osteoporosis model

S Kim, H Lee, J Hong, SHL Kim, E Kwon… - Advanced …, 2023 - Wiley Online Library
The onset of osteoporosis leads to a gradual decrease in bone density due to an imbalance
between bone formation and resorption. To achieve optimal drug efficacy with minimal side …

Effect of Bifidobacterium on osteoclasts: TNF-α/NF-κB inflammatory signal pathway-mediated mechanism

Y Wu, Y Yang, L Wang, Y Chen, X Han, L Sun… - Frontiers in …, 2023 - frontiersin.org
Osteoporosis is a systemic multifactorial bone disease characterized by low bone quality
and density and bone microstructure damage, increasing bone fragility and fracture …