Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors
I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …
Protein kinase CK2: a potential therapeutic target for diverse human diseases
CK2 is a constitutively active Ser/Thr protein kinase, which phosphorylates hundreds of
substrates, controls several signaling pathways, and is implicated in a plethora of human …
substrates, controls several signaling pathways, and is implicated in a plethora of human …
CFTR modulators: the changing face of cystic fibrosis in the era of precision medicine
M Lopes-Pacheco - Frontiers in pharmacology, 2020 - frontiersin.org
Cystic fibrosis (CF) is a lethal inherited disease caused by mutations in the CF
transmembrane conductance regulator (CFTR) gene, which result in impairment of CFTR …
transmembrane conductance regulator (CFTR) gene, which result in impairment of CFTR …
CFTR protein: not just a chloride channel?
LS Hanssens, J Duchateau, GJ Casimir - Cells, 2021 - mdpi.com
Cystic fibrosis (CF) is a recessive genetic disease caused by mutations in a gene encoding
a protein called Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). The CFTR …
a protein called Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). The CFTR …
Physiological mechanisms determining eccrine sweat composition
Purpose The purpose of this paper is to review the physiological mechanisms determining
eccrine sweat composition to assess the utility of sweat as a proxy for blood or as a potential …
eccrine sweat composition to assess the utility of sweat as a proxy for blood or as a potential …
Folding and misfolding of human membrane proteins in health and disease: from single molecules to cellular proteostasis
Advances over the past 25 years have revealed much about how the structural properties of
membranes and associated proteins are linked to the thermodynamics and kinetics of …
membranes and associated proteins are linked to the thermodynamics and kinetics of …
Structure, gating, and regulation of the CFTR anion channel
The cystic fibrosis transmembrane conductance regulator (CFTR) belongs to the ATP
binding cassette (ABC) transporter superfamily but functions as an anion channel crucial for …
binding cassette (ABC) transporter superfamily but functions as an anion channel crucial for …
Invited review: human air-liquid-interface organotypic airway tissue models derived from primary tracheobronchial epithelial cells—overview and perspectives
X Cao, JP Coyle, R Xiong, Y Wang, RH Heflich… - In Vitro Cellular & …, 2021 - Springer
The lung is an organ that is directly exposed to the external environment. Given the large
surface area and extensive ventilation of the lung, it is prone to exposure to airborne …
surface area and extensive ventilation of the lung, it is prone to exposure to airborne …
Cellular compartmentalization, glutathione transport and its relevance in some pathologies
H Vázquez-Meza, MM Vilchis-Landeros… - Antioxidants, 2023 - mdpi.com
Reduced glutathione (GSH) is the most abundant non-protein endogenous thiol. It is a
ubiquitous molecule produced in most organs, but its synthesis is predominantly in the liver …
ubiquitous molecule produced in most organs, but its synthesis is predominantly in the liver …
The therapeutic importance of acid-base balance
BN Quade, MD Parker, R Occhipinti - Biochemical pharmacology, 2021 - Elsevier
Baking soda and vinegar have been used as home remedies for generations and today we
are only a mouse-click away from claims that baking soda, lemon juice, and apple cider …
are only a mouse-click away from claims that baking soda, lemon juice, and apple cider …