Skeletal muscle contains intramyocellular lipid droplets within the cytoplasm of myocytes as
well as intermuscular adipocytes. These depots exhibit physiological and pathological …

Background Diabetes is associated with increased fracture risk but we do not know what
affects this risk. We investigated the risk of hip and non-vertebral fractures in diabetes and …

Recent scientific evidence has shown an increased risk of fractures in patients with obesity,
especially in those with a higher visceral adipose tissue content. This contradicts the old …

Aims/hypothesis Diabetes mellitus is associated with increased fracture risk in women but
few studies are available in men. To evaluate the relationship between diabetes and …

Fracture risk is significantly increased in both type 1 and type 2 diabetes, and individuals
with diabetes experience worse fracture outcomes than normoglycemic individuals. Factors …

Background Several hypotheses proposed to explain the worse prognosis for older
melanoma patients include different tumor biology and diminished host response. If the latter …

People with rheumatoid arthritis (RA) have both disease-specific risk factors for osteoporosis
and fractures in addition to those that affect the general population. Disease specific risks …

Identification of cost-effective interventions to maintain muscle mass, muscle strength, and
physical performance during muscle wasting and aging is an important public health …

Background Many physiological and/or pathological conditions lead to muscle
deconditioning, a well‐described phenomenon characterized by a loss of strength and …

Skeletal fracture has recently emerged as a complication of obesity. Given the normal or
better than normal bone mineral density (BMD), the skeletal fragility of these patients …