Testicular torsion–detorsion and potential therapeutic treatments: A possible role for ischemic postconditioning

S Shimizu, P Tsounapi, F Dimitriadis… - … Journal of Urology, 2016 - Wiley Online Library
Testicular torsion is a common urological emergency among adolescent boys and young
men. Rotation of the testis and twisting of the spermatic cord rapidly leads to ischemia …

Frontiers in pediatric testicular torsion: An integrated review of prevailing trends and management outcomes

TS Osumah, M Jimbo, CF Granberg… - Journal of Pediatric …, 2018 - Elsevier
Testicular torsion remains the most frequent cause of testicular ischemia, especially in
adolescents and young adults. Timely diagnosis and intervention are keys to saving the …

Protective effects of the hydroalcoholic extract of Fumaria parviflora on testicular injury induced by torsion/detorsion in adult rats

M Shokoohi, H Shoorei, M Soltani… - Andrologia, 2018 - Wiley Online Library
This study was designed to determine the effects of daily oral administration (250 mg/kg) of
the hydroalcoholic extract of Fumaria parviflora (FP) for 14 days on the sperm parameters …

Protective effects of crocin on testicular torsion/detorsion in rats

V Ganjiani, N Ahmadi, MR Divar, H Sharifiyazdi… - Theriogenology, 2021 - Elsevier
Oxidative stress, caused by extreme accumulation of un-scavenged reactive oxygen
species, plays an integral role in the Ischemia-Reperfusion (I/R) injury to the testicles …

Astaxanthin protects testicular tissue against torsion/detorsion-induced injury via suppressing endoplasmic reticulum stress in rats

S Demir, IO Kazaz, G Kerimoglu… - Journal of …, 2022 - Taylor & Francis
Background The aim of this study was to investigate the effects of astaxanthin (ASX) on
testicular torsion/detorsion (T/D) damage in rats in terms of oxidative stress and endoplasmic …

A comprehensive insight into the anti-inflammatory properties of dapsone

M Khalilzadeh, M Shayan, S Jourian, M Rahimi… - Naunyn-Schmiedeberg's …, 2022 - Springer
Abstract The 4, 4′-diaminodiphenyl sulfone (DDS), also known as dapsone, is traditionally
used as a potent anti-bacterial agent in clinical management of leprosy. For decades …

Beneficial effects of dapsone on ischemia/reperfusion injury following torsion/detorsion in ipsilateral and contralateral testes in rat

P Dejban, N Rahimi, N Takzare, M Jahansouz… - Theriogenology, 2019 - Elsevier
Testicular torsion is a serious urologic emergency and one of the causes of infertility in
males. Hence, prompt diagnosis and treatment are important to prevent testicular damages …

Idebenone regulates sirt1/Nrf2/TNF-α pathway with inhibition of oxidative stress, inflammation, and apoptosis in testicular torsion/detorsion in juvenile rats

WY Abdelzaher, G Mostafa-Hedeab… - Human & …, 2022 - journals.sagepub.com
Testicular torsion is an emergency, mainly in newborn and adolescent males, resulting in
testicular ischemia. The current study aimed to evaluate the effect of Idebenone (IDE) on …

Effect of Syzygium aromaticum (clove) extract on seminiferous tubules and oxidative stress after testicular torsion in adult rats

M Moghimian, SH Abtahi-Evari, M Shokoohi… - Physiology and …, 2017 - ppj.phypha.ir
Introduction: The aim was to investigate the protective effect of the Syzygium aromaticum
extract on damaged tissues and the oxidative stress after testicular torsion. Methods: Rats …

Milrinone ameliorates ischaemia‐reperfusion injury in experimental testicular torsion/detorsion rat model

E Kölükçü, D Atılgan, N Uluocak, FA Deresoy… - Andrologia, 2021 - Wiley Online Library
This experimental study aims to evaluate the efficacy of milrinone against ischaemia‐
reperfusion injury due to testicular torsion/detorsion. Group 1 was defined as the control …