Plumbagin is one of the simplest plant secondary metabolite of three major phylogenic
families viz. Plumbaginaceae, Droseraceae, and Ebenceae, and exhibits highly potent …

Bone diseases include a wide group of skeletal-related disorders that cause mobility
limitations and mortality. In some cases, eg, in osteosarcoma (OS) and metastatic bone …

Cancer is one of the most common deadly diseases and remains as one of the leading
causes of death worldwide. High mortality and incidence make it an important public health …

While there has been extensive development of anti-cancer drugs for treatment of prostate
cancer, the therapeutic efficacy of such drugs remains inadequate in many cases. Here, we …

Inhibitors of histone deacetylases have been approved for clinical application in cancer
treatment. On the other hand, histone acetyltransferase (HAT) inhibitors have been less …

Abstract Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone) is a naturally occurring
phytochemical, mainly found in the roots of the Plumbago zeylanica L. Plumbagin (PLB) …

Plumbagin is a naphthoquinone derived yellow crystalline phytochemical. Plumbagin has a
wide range of biological effects including cytotoxicity against cancer cells both in vitro and in …

Cancer is a deadly disease, which has significantly increased in both developed and
developing nations. Treatment of cancer utilizing radiotherapy or chemotherapy actuates a …

Prostate cancer is a heterogeneous disease, the second deadliest malignancy in men and
the most commonly diagnosed cancer among men. Traditional plants have been applied to …

Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone; PLB), a naturally occurring
naphthoquinone isolated from the roots of Plumbaginaceae plants, has been reported to …