[HTML][HTML] The role of emotions in cancer patients' decision-making

K Mazzocco, M Masiero, MC Carriero… - …, 2019 - ncbi.nlm.nih.gov
Objective The objective of the present review is to provide a brief overview of research on
decision making and cancer with a specific focus on the role of emotions. Method Thirty-nine …

[HTML][HTML] Clinical applications of polygenic breast cancer risk: a critical review and perspectives of an emerging field

T Yanes, MA Young, B Meiser, PA James - Breast Cancer Research, 2020 - Springer
Polygenic factors are estimated to account for an additional 18% of the familial relative risk
of breast cancer, with those at the highest level of polygenic risk distribution having a least a …

Racial disparities in BRCA testing and cancer risk management across a population‐based sample of young breast cancer survivors

D Cragun, A Weidner, C Lewis, D Bonner, J Kim… - Cancer, 2017 - Wiley Online Library
BACKGROUND Breast cancer (BC) disparities may widen with genomic advances. The
authors compared non‐Hispanic white (NHW), black, and Hispanic BC survivors for 1) …

Randomized Noninferiority Trial of Telephone Delivery of BRCA1/2 Genetic Counseling Compared With In-Person Counseling: 1-Year Follow-Up

AY Kinney, LE Steffen, BH Brumbach… - Journal of Clinical …, 2016 - ascopubs.org
Purpose The ongoing integration of cancer genomic testing into routine clinical care has led
to increased demand for cancer genetic services. To meet this demand, there is an urgent …

[HTML][HTML] Decision making for breast cancer prevention among women at elevated risk

TJ Padamsee, CE Wills, LD Yee, ED Paskett - Breast Cancer Research, 2017 - Springer
Several medical management approaches have been shown to be effective in preventing
breast cancer and detecting it early among women at elevated risk: 1) prophylactic …

Risk management options elected by women after testing positive for a BRCA mutation

C Garcia, J Wendt, L Lyon, J Jones, RD Littell… - Gynecologic …, 2014 - Elsevier
Objective To assess the uptake of risk-reducing options for the management of ovarian and
breast cancer risk in BRCA mutation carriers in a large community based integrated health …

Variants of uncertain significance in BRCA testing: evaluation of surgical decisions, risk perception, and cancer distress

JO Culver, CD Brinkerhoff, J Clague, K Yang… - Clinical …, 2013 - Wiley Online Library
Studies suggest that patients carrying a BRCA variant of uncertain significance (VUS) may
have lingering confusion concerning results interpretation. Counseling for uninformative …

Systemic barriers to risk-reducing interventions for hereditary cancer syndromes: implications for health care inequities

KF Mittendorf, S Knerr, TL Kauffman… - JCO Precision …, 2021 - ascopubs.org
Hereditary cancer syndromes result from germline genetic alterations predisposing
individuals to higher lifetime cancer risk than the general population. Hereditary cancer …

A role for common genomic variants in the assessment of familial breast cancer

S Sawyer, G Mitchell, J McKinley… - Journal of clinical …, 2012 - ascopubs.org
Purpose Genome-wide association studies have identified common genomic variants
associated with increased susceptibility to breast cancer. In the general population, the risk …

[HTML][HTML] Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing

U Francke, C Dijamco, AK Kiefer, N Eriksson, B Moiseff… - PeerJ, 2013 - peerj.com
Background. Inherited BRCA gene mutations convey a high risk for breast and ovarian
cancer, but current guidelines limit BRCA mutation testing to women with early-onset cancer …