Neuroinflammation was initially thought of as a consequence of neurodegenerative disease
pathology, but more recently it is becoming clear that it plays a significant role in the …

Infiltration of memory CD4+ T cells in synovial joints of Rheumatoid Arthritis (RA) patients
has been reported since decades. Moreover, several genome wide association studies …

Historically, vitamin D has been associated with the regulation of bone metabolism.
However, increasing evidence demonstrates a strong association between vitamin D …

Objective Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease, and its
pathogenetic mechanism is far from being understood. In this study, we aimed to explore the …

As the thymus involutes during aging, the T‐cell pool has to be maintained by the periodic
expansion of preexisting T cells during adulthood. A conundrum is that repeated episodes of …

Aging is inevitable. Along with reduced ability to maintain the homeostasis of various
biological processes, aging gradually deteriorates overall health. Extensive research on the …

Multiple sclerosis (MS) is a chronic inflammatory disease that is characterized by leukocyte
infiltration and subsequent axonal damage, demyelinating inflammation, and formation of …

In chronic inflammatory diseases of the central nervous system (CNS), immune cells
persisting behind the blood-brain barrier are supposed to promulgate local tissue …

BACKGROUND. Lymphocytes contribute to ischemia/reperfusion (I/R) injury in several
organ systems, but their relevance in ST elevation myocardial infarction (STEMI) is …

Recently it has become apparent that microglia play a role not only in responding to insults
within the central nervous system but also in responding to changes in synaptic activity and …