Biological aging processes underlying cognitive decline and neurodegenerative disease
MM Gonzales, VR Garbarino, E Pollet… - The Journal of …, 2022 - Am Soc Clin Investig
Alzheimer's disease and related dementias (ADRD) are among the top contributors to
disability and mortality in later life. As with many chronic conditions, aging is the single most …
disability and mortality in later life. As with many chronic conditions, aging is the single most …
Revisiting the neurovascular unit
S Schaeffer, C Iadecola - Nature neuroscience, 2021 - nature.com
The brain is supplied by an elaborate vascular network that originates extracranially and
reaches deep into the brain. The concept of the neurovascular unit provides a useful …
reaches deep into the brain. The concept of the neurovascular unit provides a useful …
Targeting autoregulation-guided cerebral perfusion pressure after traumatic brain injury (COGiTATE): a feasibility randomized controlled clinical trial
J Tas, E Beqiri, RC van Kaam, M Czosnyka… - Journal of …, 2021 - liebertpub.com
Managing traumatic brain injury (TBI) patients with a cerebral perfusion pressure (CPP) near
to the cerebral autoregulation (CA)-guided “optimal” CPP (CPPopt) value is associated with …
to the cerebral autoregulation (CA)-guided “optimal” CPP (CPPopt) value is associated with …
The neurovasculome: key roles in brain health and cognitive impairment: a scientific statement from the American Heart Association/American Stroke Association
Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …
the aging world population. Advances in neurovascular biology have revealed an intricate …
Hypertension, neurovascular dysfunction, and cognitive impairment
MM Santisteban, C Iadecola, D Carnevale - Hypertension, 2023 - Am Heart Assoc
Hypertension affects a significant proportion of the adult and aging population and
represents an important risk factor for vascular cognitive impairment and late-life dementia …
represents an important risk factor for vascular cognitive impairment and late-life dementia …
Transfer function analysis of dynamic cerebral autoregulation: a CARNet white paper 2022 update
Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in
response to changes in perfusion pressure. Due to the challenges of measuring intracranial …
response to changes in perfusion pressure. Due to the challenges of measuring intracranial …
Losing the dogmatic view of cerebral autoregulation
Abstract In 1959, Niels Lassen illustrated the cerebral autoregulation curve in the classic
review article entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept …
review article entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept …
Vascular contributions to Alzheimer's disease
LB Eisenmenger, A Peret, BM Famakin, A Spahic… - Translational …, 2023 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia and is characterized by
progressive neurodegeneration and cognitive decline. Understanding the pathophysiology …
progressive neurodegeneration and cognitive decline. Understanding the pathophysiology …
Posterior reversible encephalopathy syndrome
RG Geocadin - New England Journal of Medicine, 2023 - Mass Medical Soc
Posterior Reversible Encephalopathy Syndrome | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …
content The New England Journal of Medicine homepage Advanced Search SEARCH …
New insights into cerebrovascular pathophysiology and hypertension
AJS Webb, DJ Werring - Stroke, 2022 - Am Heart Assoc
Despite advances in acute management and prevention of cerebrovascular disease, stroke
and vascular cognitive impairment together remain the world's leading cause of death and …
and vascular cognitive impairment together remain the world's leading cause of death and …