Background: Complex regional pain syndrome (CRPS) is characterized by signs and
symptoms of peripheral inflammation, which leads to peripheral neural sensitization …

Intravenous (iv) paracetamol is used as 1‐g infusions with a maximal daily dose of 4 g/day.
However, a higher initial analgesic dose could be of interest in the immediate postoperative …

Human experimental pain models are widely used to study drug effects under controlled
conditions. However, efforts to improve both animal and human experimental model …

Background: The aim of this prospective, randomized, placebo-controlled study was to
compare the effects of ketamine and paracetamol on preventing remifentanil induced …

Background Persistent pain is a challenging clinical problem after breast cancer treatment.
After surgery, inflammatory pain and nociceptive input from nerve injury induce central …

The anti‐inflammatory effects of the methanol extract of the roots of Morinda officinalis
(MEMO)(Rubiaceae) were evaluated in‐vitro and in‐vivo. The effects of MEMO on …

Study Design. A randomized, double-blind, placebo-controlled study, with a six-month follow-
up period. Objectives. The aim of this study was to test the hypothesis that a 72-hour dose of …

This study tested a modified experimental model of heat-induced hyperalgesia, which
improves the efficacy to induce primary and secondary hyperalgesia and the efficacy-to …

The analysis of drug's influence on peripheral and central sensitisation can give useful
information about its mode of action and can lead to more efficacy in the treatment of pain …

OBJECTIVE:: The authors explored the use of continuous postoperative subpleural
paravertebral ropivacaine alone combined with intraoperative S (+)-ketamine or …