Psychiatric disorders, including major depressive disorder (MDD), bipolar disorder (BD) and
schizophrenia, affect a significant percentage of the world population. These disorders are …

Posterior reversible encephalopathy syndrome is a rare clinicoradiological entity
characterized by typical MRI findings located in the occipital and parietal lobes, caused by …

We introduce an approach to identify disease-relevant tissues and cell types by analyzing
gene expression data together with genome-wide association study (GWAS) summary …

Individuals with psychiatric disorders have elevated rates of autoimmune comorbidity and
altered immune signaling. It is unclear whether these altered immunological states have a …

About one-third of people with major depressive disorder (MDD) fail at least two
antidepressant drug trials at 1 year. Together with clinical and experimental evidence …

Bipolar disorder (BD) is a complex disorder with a range of presentations. BD is defined by
the presentation of symptoms of mania or depression, with classification dependent on …

Bipolar Disorder (BD) has been conceptualized as both a cyclic and a progressive disorder.
Mechanisms involved in neuroprogression in BD remain largely unknown although several …

Bipolar disorder (BD) is characterized by mood changes, including recurrent manic,
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …

Abstract Background The relationship between Toxoplasma gondii infection and the
development of bipolar disorder (BD) has long been investigated, yet to date it is still poorly …

Bipolar disorder (BD) is a distinctly heterogeneous and multifactorial disorder with a high
individual and social burden. Immune pathway dysregulation is an important …