Hydrogen sulfide (H2S) has emerged as a gaseous signalling molecule with crucial
implications for cardiovascular health. H2S is involved in many biological functions …

Critical limb ischemia (CLI) constitutes the most severe form of peripheral arterial disease
(PAD), it is characterized by progressive blockade of arterial vessels, commonly correlated …

Formation of arterial vasculature, here termed arteriogenesis, is a central process in
embryonic vascular development as well as in adult tissues. Although the process of …

Although surgical and endovascular revascularization can be performed in peripheral
arterial disease (PAD), 40% of patients with critical limb ischemia do not have a …

Highlights•The goal of angiogenesis in PAD is formation of collateral circulation.•It may be
particularly useful for patients no deemed candidates for revascularization.•Angiogenic …

Thromboangiitis obliterans (Buerger's disease) : Annals of Medicine and Surgery
Thromboangiitis obliterans (Buerger's disease) : Annals of Medicine and Surgery Log in or …

Stem cell transplantation has been extensively explored to promote ischemic limb
vascularization and skeletal muscle regeneration. Yet the therapeutic efficacy is low due to …

Peripheral arterial disease (PAD) usually results from atherosclerosis and associated
thrombosis and limits blood supply to the lower limbs. Common presenting symptoms …

Critical limb ischemia (CLI) is the most severe clinical manifestation of peripheral arterial
disease (PAD), resulting in the total or partial loss of limb function. Although the conventional …

Stem cell therapy is one of the most promising strategies to restore blood perfusion and
promote muscle regeneration in ischemic limbs. Yet its therapeutic efficacy remains low …