Autophagy regulators in cancer

J Zhang, Q Xiang, M Wu, YZ Lao, YF Xian… - International Journal of …, 2023 - mdpi.com
Autophagy plays a complex impact role in tumor initiation and development. It serves as a
double-edged sword by supporting cell survival in certain situations while also triggering …

[HTML][HTML] Comprehensive evaluation of cell death-related genes as novel diagnostic biomarkers for breast cancer

X Shi, H Ding, J Tao, Y Zhu, X Zhang, G He, J Yang… - Heliyon, 2023 - cell.com
Background Breast cancer (BRCA) ranks first among cancers in terms of incidence and
mortality rates in women, primarily owing to metastasis, chemo-resistance, and …

[HTML][HTML] Exploring monocarboxylate transporter inhibition for cancer treatment

T Koltai, L Fliegel - Exploration of Targeted Anti-tumor Therapy, 2024 - ncbi.nlm.nih.gov
Cells are separated from the environment by a lipid bilayer membrane that is relatively
impermeable to solutes. The transport of ions and small molecules across this membrane is …

Autophagy flux in bladder cancer: Cell death crosstalk, drug and nanotherapeutics

K Liu, H Chen, Y Li, B Wang, Q Li, L Zhang, X Liu… - Cancer Letters, 2024 - Elsevier
Autophagy, a self-digestion mechanism, has emerged as a promising target in the realm of
cancer therapy, particularly in bladder cancer (BCa), a urological malignancy characterized …

TRIM11 promotes cell proliferation of non‐small cell lung cancer through the inhibition of ferroptosis by AMPK

Z Liang, J Li, G Zhang, M Chen - The Clinical Respiratory …, 2023 - Wiley Online Library
Lung cancer is one of the leading causes of cancer‐related deaths worldwide, with non‐
small cell lung cancer (NSCLC) being the most prevalent type. This study investigates the …

Monocarboxylate transporter 4 promotes the migration of non‑cancerous L929 fibroblast cells by activating the IGF1/IGF1R/PIK3R3/SGK1 axis

X Zhou, S Wang, Y Li, H Zhao, X Han… - Oncology …, 2023 - spandidos-publications.com
The tumor microenvironment (TME) and Warburg effect are critical for the regulation of tumor
metastasis. The monocarboxylate transporter (MCT) family members, particularly MCT4 …