Background: The Chinese mitten crab, Eriocheir sinensis (E. sinensis), is a popular crab
species in both domestic and foreign markets. Trash fish are essential for E. sinensis …

Simple Summary Neuregulin is a growth factor that has been shown to prevent adverse
remodeling in the heart and may represent a therapeutic for patients with systolic heart …

EGFR is one of the key oncogenes subjected to targeted therapy for several cancers, as it is
known to be amplified and/or mutated in up to 40% of malignant gliomas. EFEMP1, a fibulin …

Breast cancer is a leading cause of cancer mortality. In particular, triple negative breast
cancer (TNBC) comprise a heterogeneous group of basal-like tumors lacking estrogen …

De-regulated EFEMP1 gene expression in solid tumors has been widely reported with
conflicting roles. We dissected EFEMP1 to identify domains responsible for its cell context …

Papillary thyroid carcinoma (PTC) is the most common type of thyroid carcinoma, and our
understanding of its pathogenesis is incomplete. To elucidate the mechanisms underlying …

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer.
Several previous studies have shown that fibulin-3 participates in the occurrence and …

RESULTS: Preoperative serum fibulin-3 levels were significantly lower in the group of
patients with colon cancer (mean, 35.91 ng/mL; range, 10-73 ng/mL) compared with the …

The EFEMP1 coding region extends over a genomic interval of 56485 bp and comprises 10
exons. EFEMP1 proximal promoter lacks TATA or CAAT regulatory boxes and is rich with …

Anticancer chemotherapy (CT) produces non-desirable effects on normal healthy cells and
tissues. Oxaliplatin is widely used in the treatment of colorectal cancer and responsible for …