Increasing evidence has indicated that long noncoding RNAs (lncRNAs) play various
important roles in the development of cancers. The widespread applications of ribosome …

Nucleic acid binding proteins regulate transcription, splicing, RNA stability, RNA localization,
and translation, together tailoring gene expression in response to stimuli. Upon discovery …

Abstract Aim Recently, miR‐27b‐5p was shown to be abundantly expressed in extracellular
vehicles (EVs) from the inflammatory microenvironment. This study determined the role of …

Sox proteins are known as crucial transcription factors for many developmental processes
and for a wide range of common diseases. They were believed to specifically bind and bend …

Introduction LncRNAs play important roles in multiple diseases including asthma, while
there are a few reports on the role of lncRNA H19 about asthma. This study aimed to …

There is a growing body of evidence that a substantial number of protein domains identified
as DNA-binding also interact with RNA to regulate biological processes. Several recent …

Background SOX2 is a determinant transcription factor that governs the balance between
stemness and differentiation by influencing transcription and splicing programs. The role of …

Bone marrow mesenchymal stem cells (BMSCs) possess the potential to differentiate into
cartilage cells. Long noncoding RNA (lncRNAs) urothelial carcinoma associated 1 (UCA1) …

Exploring the mechanism of self-renewal and pluripotency maintenance of human
embryonic stem cells (hESCs) is of great significance in basic research and clinical …

The embryonic stem cell-(ESC) specific transcription factor Oct4 is a well-known master
regulator of pluripotency. The aim of this study was to identify upstream regulators of Oct4 …