[HTML][HTML] The role of gut microbiota in liver regeneration

Z Xu, N Jiang, Y Xiao, K Yuan, Z Wang - Frontiers in Immunology, 2022 - frontiersin.org
The liver has unique regeneration potential, which ensures the continuous dependence of
the human body on hepatic functions. As the composition and function of gut microbiota has …

[HTML][HTML] Cell therapy in end-stage liver disease: replace and remodel

XH Hu, L Chen, H Wu, YB Tang, QM Zheng… - Stem Cell Research & …, 2023 - Springer
Liver disease is prevalent worldwide. When it reaches the end stage, mortality rises to 50%
or more. Although liver transplantation has emerged as the most efficient treatment for end …

[HTML][HTML] Adipose-derived stem cells (ADSCs) supplemented with hepatocyte growth factor (HGF) attenuate hepatic stellate cell activation and liver fibrosis by inhibiting …

S Gharbia, SR Nazarie, S Dinescu, C Balta, H Herman… - Cells, 2022 - mdpi.com
Liver fibrosis can develop on the background of hyperglycemia in diabetes mellitus.
However, xenobiotic-related factors may accelerate diabetes-associated liver fibrosis. In this …

[HTML][HTML] 肝细胞生长因子修饰的人脂肪间充质干细胞外泌体对糖尿病小鼠全层皮肤缺损的作用

曹涛, 肖丹, 计鹏, 张智, 蔡维霞, 韩超… - 中华烧伤与创面 …, 2022 - zhsszz.xml-journal.net
目的探讨肝细胞生长因子(HGF) 修饰的人脂肪间充质干细胞(ADSC) 外泌体对糖尿病小鼠全层
皮肤缺损创面的作用及其机制. 方法采用实验研究方法. 取2021 年2—5 月于空军军医大学第一 …

[HTML][HTML] Targeting MET in Non-Small Cell Lung Cancer (NSCLC): A New Old Story?

CC Spagnolo, G Ciappina, E Giovannetti… - International journal of …, 2023 - mdpi.com
In recent years, we have seen the development and approval for clinical use of an
increasing number of therapeutic agents against actionable oncogenic drivers in metastatic …

Age‐related nitration/dysfunction of myogenic stem cell activator HGF

A Elgaabari, N Imatomi, H Kido, T Nakashima… - Aging cell, 2024 - Wiley Online Library
Mechanical perturbation triggers activation of resident myogenic stem cells to enter the cell
cycle through a cascade of events including hepatocyte growth factor (HGF) release from its …

[HTML][HTML] AAV9-HGF cooperating with TGF-beta/Smad inhibitor attenuates silicosis fibrosis via inhibiting ferroptosis

R Bao, Q Wang, M Yu, Y Zeng, S Wen, T Liu… - Biomedicine & …, 2023 - Elsevier
Silicosis is a devastating interstitial lung disease characterized by silicon nodules and
diffuse pulmonary fibrosis. To date, inefficient therapy is still a challenge of this disease due …

[HTML][HTML] Heterogeneity of hepatocyte dynamics restores liver architecture after chemical, physical or viral damage

I Ruz-Maldonado, JT Gonzalez, H Zhang, J Sun… - Nature …, 2024 - nature.com
Midlobular hepatocytes are proposed to be the most plastic hepatic cell, providing a
reservoir for hepatocyte proliferation during homeostasis and regeneration. However, other …

[HTML][HTML] New and Old Key Players in Liver Cancer

ÁM Cuesta, N Palao, P Bragado… - International Journal of …, 2023 - mdpi.com
Liver cancer represents a major health problem worldwide with growing incidence and high
mortality, hepatocellular carcinoma (HCC) being the most frequent. Hepatocytes are likely …

HGF secreted by menstrual blood-derived endometrial stem cells ameliorates non-alcoholic fatty liver disease through downregulation of hepatic Rnf186

J Du, Y Jiang, X Liu, X Ji, B Xu, Y Zhang, Y Liu… - Stem Cells, 2023 - academic.oup.com
Mesenchymal stem cells (MSCs) have been demonstrated to protect against fatty liver
diseases, but the mechanism is still not clear. Menstrual blood-derived endometrial stem …