[HTML][HTML] Evaluation of the Pfs25-IMX313/Matrix-M malaria transmission-blocking candidate vaccine in endemic settings

C Mulamba, C Williams, K Kreppel, JB Ouedraogo… - Malaria Journal, 2022 - Springer
Malaria control relies heavily on the use of anti-malarial drugs and insecticides against
malaria parasites and mosquito vectors. Drug and insecticide resistance threatens the …

[HTML][HTML] ApiAP2 gene-network regulates gametocytogenesis in Plasmodium parasites

E Quansah, F Pappoe, J Shen, M Liu, S Yang… - Cellular …, 2022 - hindawi.com
Malaria is a mosquito-borne infectious disease, caused by unicellular Apicomplexan
protozoa of the genus Plasmodium. The sexual stage of Plasmodium is one of the most …

[HTML][HTML] Targeting Gametocytes of the Malaria Parasite Plasmodium falciparum in a Functional Genomics Era: Next Steps

J Chawla, J Oberstaller, JH Adams - Pathogens, 2021 - mdpi.com
Mosquito transmission of the deadly malaria parasite Plasmodium falciparum is mediated by
mature sexual forms (gametocytes). Circulating in the vertebrate host, relatively few …

[HTML][HTML] HIV-1 impact on malaria transmission: a complex and relevant global health concern

A Roberds, E Ferraro, S Luckhart… - Frontiers in Cellular and …, 2021 - frontiersin.org
Malaria/HIV-1 co-infection has become a significant public health problem in the tropics
where there is geographical overlap of the two diseases. It is well described that co-infection …

[HTML][HTML] Functional food for the stimulation of the immune system against malaria

T Bamgbose, AR Anvikar, P Alberdi… - Probiotics and …, 2021 - Springer
Drug resistance has become a threat to global health, and new interventions are needed to
control major infectious diseases. The composition of gut microbiota has been linked to …

[HTML][HTML] Progress in the development of subunit vaccines against malaria

M Skwarczynski, S Chandrudu, B Rigau-Planella… - Vaccines, 2020 - mdpi.com
Malaria is a life-threatening disease and one of the main causes of morbidity and mortality in
the human population. The disease also results in a major socio-economic burden. The …

[HTML][HTML] The search of a malaria vaccine: the time for modified immuno-potentiating probes

JM Lozano, Z Rodríguez Parra, S Hernández-Martínez… - Vaccines, 2021 - mdpi.com
Malaria is a deadly disease that takes the lives of more than 420,000 people a year and is
responsible for more than 229 million clinical cases globally. In 2019, 95% of malaria …

[HTML][HTML] Immune selection suppresses the emergence of drug resistance in malaria parasites but facilitates its spread

AOB Whitlock, JJ Juliano, N Mideo - PLOS Computational Biology, 2021 - journals.plos.org
Although drug resistance in Plasmodium falciparum typically evolves in regions of low
transmission, resistance spreads readily following introduction to regions with a heavier …

Deciphering host immunity to malaria using systems immunology

C Loiseau, MM Cooper, DL Doolan - Immunological Reviews, 2020 - Wiley Online Library
A century of conceptual and technological advances in infectious disease research has
changed the face of medicine. However, there remains a lack of effective interventions and a …

[HTML][HTML] Transcriptional Profiles Analysis of COVID-19 and Malaria Patients Reveals Potential Biomarkers in Children

N Lambert, JA Kengne-Ouafo, WM Rissy, U Diane… - BioRxiv, 2022 - ncbi.nlm.nih.gov
The clinical presentation overlap between malaria and COVID-19 poses special challenges
for rapid diagnosis in febrile children. In this study, we collected RNA-seq data of children …