The neurovascular unit (NVU) is a conceptual framework that has been proposed to better
explain the relationships between the neural cells and blood vessels in the human brain …

Alzheimer's disease (AD) is a complex and progressive disease, which affects millions of
people around the world. Despite the many efforts over the years to find efficient …

The blood-brain barrier (BBB) is a fundamental component of the central nervous system
(CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain …

A growing body of evidence has demonstrated a link between Alzheimer disease (AD) and
epilepsy. Late-onset epilepsy and epileptiform activity can precede cognitive deterioration in …

Alzheimer's disease (AD) is the most common progressive and irreversible
neurodegeneration characterized by the impairment of memory and cognition. Despite years …

Increasing evidence has suggested a link between cerebrovascular disease and the
cognitive impairment associated with Alzheimer's disease. However, detailed descriptions of …

Neurodegenerative diseases (NDDs) causing cognitive impairment and dementia are
difficult to treat due to the lack of understanding of primary initiating factors. Meanwhile …

Adipose tissue has recently been recognized as an important endocrine organ that plays a
crucial role in energy metabolism and in the immune response in many metabolic tissues …

Alzheimer's disease (AD) is a neurodegenerative disease representing the most common
type of dementia worldwide. The early diagnosis of AD is very difficult to achieve due to its …

Abstract Background Endothelial cells (ECs) and pericytes (PCs) are crucial components of
the vascular system, with ECs lining the inner layer of blood vessels and PCs surrounding …