Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance

HS Tuli, S Mittal, D Aggarwal, G Parashar… - Seminars in Cancer …, 2021 - Elsevier
In the last few decades, targeting cancer by the use of dietary phytochemicals has gained
enormous attention. The plausible reason and believe or mind set behind this fact is …

Role of Hedgehog and Hippo signaling pathways in cancer: a special focus on non-coding RNAs

U Sharma, HS Tuli, V Uttam, R Choudhary… - Pharmacological …, 2022 - Elsevier
Despite advanced clinical and translational oncology research, mortality rates are still
increasing worldwide. Recently, a class of non-coding RNAs (ncRNAs), such as microRNAs …

Long noncoding RNA SNHG12 promotes tumour progression and sunitinib resistance by upregulating CDCA3 in renal cell carcinoma

Y Liu, G Cheng, Z Huang, L Bao, J Liu, C Wang… - Cell death & …, 2020 - nature.com
Renal cell carcinoma (RCC) is one of the most frequently observed malignant tumours in the
urinary system and targeted drug resistance is quite common in RCC. Long noncoding RNA …

Molecular mechanism of lncRNA SNHG12 in immune escape of non-small cell lung cancer through the HuR/PD-L1/USP8 axis

Y Huang, L Xia, X Tan, J Zhang, W Zeng, B Tan… - Cellular & Molecular …, 2022 - Springer
Background The pivotal role of long noncoding RNAs (lncRNAs) in cancer immune
responses has been well established. This study was conducted with the aim of exploring …

Weighted gene co-expression network analysis identifies critical genes in the development of heart failure after acute myocardial infarction

X Niu, J Zhang, L Zhang, Y Hou, S Pu, A Chu… - Frontiers in …, 2019 - frontiersin.org
Background: The development of heart failure (HF) remains a common complication
following an acute myocardial infarction (AMI), and is associated with substantial adverse …

LncRNA MIAT correlates with immune infiltrates and drug reactions in hepatocellular carcinoma

L Peng, Y Chen, Q Ou, X Wang, N Tang - International …, 2020 - Elsevier
Long non-coding RNA (lncRNA) is a kind of important molecules involved in the formation of
immune landscape in tumor microenvironment. However, there are few studies on the …

SnoRNA in cancer progression, metastasis and immunotherapy response

J van der Werf, CV Chin, NI Fleming - Biology, 2021 - mdpi.com
Simple Summary A much larger number of small nucleolar RNA (snoRNA) have been found
encoded within our genomes than we ever expected to see. The activities of the snoRNAs …

Interplay between SOX9 transcription factor and microRNAs in cancer

M Ashrafizadeh, A Zarrabi, S Orouei, A Zabolian… - International journal of …, 2021 - Elsevier
SOX transcription factors are critical regulators of development, homeostasis and disease
progression and their dysregulation is a common finding in various cancers. SOX9 belongs …

Crosstalk between lncRNAs in the apoptotic pathway and therapeutic targets in cancer

N Ebrahimi, S Parkhideh, S Samizade… - Cytokine & growth factor …, 2022 - Elsevier
The assertion that a significant portion of the mammalian genome has not been translated
and that non-coding RNA accounts for over half of polyadenylate RNA have received much …

LncRNA SNHG12 in extracellular vesicles derived from carcinoma-associated fibroblasts promotes cisplatin resistance in non-small cell lung cancer cells

D Tan, G Li, P Zhang, C Peng, B He - Bioengineered, 2022 - Taylor & Francis
Non-small-cell lung cancer (NSCLC) is defined as the most universally diagnosed class of
lung cancer. Cisplatin (DDP) is an effective drug for NSCLC, but tumors are prone to drug …