[HTML][HTML] Radiation combined with immune checkpoint inhibitors for unresectable locally advanced non-small cell lung cancer: synergistic mechanisms, current state …

L Wu, Z Zhang, M Bai, Y Yan, J Yu, Y Xu - Cell Communication and …, 2023 - Springer
Until the advent of immune checkpoint inhibitors (ICIs), definitive radiotherapy (RT)
concurrently with chemotherapy was recommended for unresectable, locally advanced non …

[HTML][HTML] Molecular testing in stage I–III non-small cell lung cancer: Approaches and challenges

C Aggarwal, L Bubendorf, WA Cooper, P Illei… - Lung Cancer, 2021 - Elsevier
Precision medicine in non-small cell lung cancer (NSCLC) is a rapidly evolving area, with
the development of targeted therapies for advanced disease and concomitant molecular …

Osimertinib after Chemoradiotherapy in Stage III EGFR-Mutated NSCLC

S Lu, T Kato, X Dong, MJ Ahn, LV Quang… - New England Journal …, 2024 - drsite.nejm.org
Background Osimertinib is a recommended treatment for advanced non–small-cell lung
cancer (NSCLC) with an epidermal growth factor receptor (EGFR) mutation and as adjuvant …

Targeted treatment for unresectable EGFR mutation-positive stage III non-small cell lung cancer: Emerging evidence and future perspectives

T Kato, I Casarini, M Cobo, C Faivre-Finn… - Lung Cancer, 2023 - Elsevier
Epidermal growth factor receptor (EGFR) mutations are detected in up to one third of
patients with unresectable stage III non-small cell lung cancer (NSCLC). The current …

[HTML][HTML] Challenges of EGFR-TKIs in NSCLC and the potential role of herbs and active compounds: From mechanism to clinical practice

X Song, L Cao, B Ni, J Wang, X Qin, X Sun… - Frontiers in …, 2023 - frontiersin.org
Epidermal growth factor receptor (EGFR) mutations are the most common oncogenic driver
in non-small cell lung cancer (NSCLC). Epidermal growth factor receptor-tyrosine kinase …

Current challenges of unresectable stage III NSCLC: are we ready to break the glass ceiling of the PACIFIC trial?

J Remon, A Levy, P Singh… - Therapeutic …, 2022 - journals.sagepub.com
Consolidation anti-programmed death-ligand 1 has become a new standard of care in
unresectable stage III non-small cell lung cancer (NSCLC) following chemo-radiotherapy …

Management of locally advanced non‐small cell lung cancer: State of the art and future directions

D Miao, J Zhao, Y Han, J Zhou, X Li… - Cancer …, 2024 - Wiley Online Library
Lung cancer is the second most common and the deadliest type of cancer worldwide.
Clinically, non‐small cell lung cancer (NSCLC) is the most common pathological type of …

Clinical outcomes and radiation pneumonitis after concurrent EGFR‐tyrosine kinase inhibitors and radiotherapy for unresectable stage III non‐small cell lung cancer

K Xu, J Liang, T Zhang, Z Zhou, D Chen… - Thoracic …, 2021 - Wiley Online Library
Background Concurrent epidermal growth factor receptor‐tyrosine kinase inhibitors (EGFR‐
TKI) with radiotherapy in patients with EGFR‐mutant unresectable stage III non‐small cell …

[HTML][HTML] A multicenter retrospective study on the prognosis of stage III unresectable mutant non-small cell lung cancer with tyrosine kinase inhibitors therapy

R Wu, S Yu, J Ye, Y Wang, Z Zhao, H Liu… - Frontiers in …, 2021 - frontiersin.org
Background For unresectable stage III non-small cell lung cancer (NSCLC), concurrent
chemoradiotherapy is nowadays the standard treatment. Patients with advanced NSCLC …

[HTML][HTML] Immunotherapy progress and clinical strategy of unresectable locally advanced non-small cell lung cancer

X Zhang, J Zhang, P Liu, J Wang, K Zhao, Z Zhu… - Frontiers in …, 2023 - frontiersin.org
Non-small cell lung cancer without sensitive mutations entered the splendid era of
immunotherapy. This review aims to provide an evidence-based summary for …